Monte Carlo dose computation for IMRT optimization

W. Laub, M. Alber, M. Birkner, F. Nüsslin

Research output: Contribution to journalArticlepeer-review

56 Scopus citations


A method which combines the accuracy of Monte Carlo dose calculation with a finite size pencil-beam based intensity modulation optimization is presented. The pencil-beam algorithm is employed to compute the fluence element updates for a converging sequence of Monte Carlo dose distributions. The combination is shown to improve results over the pencil-beam based optimization in a lung tumour case and a head and neck case. Inhomogeneity effects like a broader penumbra and dose build-up regions can be compensated for by intensity modulation.

Original languageEnglish (US)
Pages (from-to)1741-1754
Number of pages14
JournalPhysics in Medicine and Biology
Issue number7
StatePublished - Jul 2000

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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