Monte Carlo dose computation for IMRT optimization

W. Laub; M. Alber; M. Birkner; F. Nüsslin

doi:10.1088/0031-9155/45/7/303

Monte Carlo dose computation for IMRT optimization

W. Laub, M. Alber, M. Birkner, F. Nüsslin

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

A method which combines the accuracy of Monte Carlo dose calculation with a finite size pencil-beam based intensity modulation optimization is presented. The pencil-beam algorithm is employed to compute the fluence element updates for a converging sequence of Monte Carlo dose distributions. The combination is shown to improve results over the pencil-beam based optimization in a lung tumour case and a head and neck case. Inhomogeneity effects like a broader penumbra and dose build-up regions can be compensated for by intensity modulation.

Original language	English (US)
Pages (from-to)	1741-1754
Number of pages	14
Journal	Physics in Medicine and Biology
Volume	45
Issue number	7
DOIs	https://doi.org/10.1088/0031-9155/45/7/303
State	Published - Jul 2000
Externally published	Yes

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging

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AB - A method which combines the accuracy of Monte Carlo dose calculation with a finite size pencil-beam based intensity modulation optimization is presented. The pencil-beam algorithm is employed to compute the fluence element updates for a converging sequence of Monte Carlo dose distributions. The combination is shown to improve results over the pencil-beam based optimization in a lung tumour case and a head and neck case. Inhomogeneity effects like a broader penumbra and dose build-up regions can be compensated for by intensity modulation.

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Monte Carlo dose computation for IMRT optimization

Abstract

ASJC Scopus subject areas

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