Monte Carlo dose computation for IMRT optimization

Wolfram Laub, M. Alber, M. Birkner, F. Nüsslin

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

A method which combines the accuracy of Monte Carlo dose calculation with a finite size pencil-beam based intensity modulation optimization is presented. The pencil-beam algorithm is employed to compute the fluence element updates for a converging sequence of Monte Carlo dose distributions. The combination is shown to improve results over the pencil-beam based optimization in a lung tumour case and a head and neck case. Inhomogeneity effects like a broader penumbra and dose build-up regions can be compensated for by intensity modulation.

Original languageEnglish (US)
Pages (from-to)1741-1754
Number of pages14
JournalPhysics in Medicine and Biology
Volume45
Issue number7
DOIs
StatePublished - Jul 2000
Externally publishedYes

Fingerprint

pencil beams
Neck
Head
Modulation
dosage
Lung
optimization
modulation
Tumors
penumbras
Neoplasms
lungs
fluence
inhomogeneity
tumors

ASJC Scopus subject areas

  • Biomedical Engineering
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Monte Carlo dose computation for IMRT optimization. / Laub, Wolfram; Alber, M.; Birkner, M.; Nüsslin, F.

In: Physics in Medicine and Biology, Vol. 45, No. 7, 07.2000, p. 1741-1754.

Research output: Contribution to journalArticle

Laub, W, Alber, M, Birkner, M & Nüsslin, F 2000, 'Monte Carlo dose computation for IMRT optimization', Physics in Medicine and Biology, vol. 45, no. 7, pp. 1741-1754. https://doi.org/10.1088/0031-9155/45/7/303
Laub, Wolfram ; Alber, M. ; Birkner, M. ; Nüsslin, F. / Monte Carlo dose computation for IMRT optimization. In: Physics in Medicine and Biology. 2000 ; Vol. 45, No. 7. pp. 1741-1754.
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