Monitoring radiofrequency catheter ablation using thermal strain imaging

Chi Hyung Seo, Douglas Stephens, Jonathan Cannata, Aaron Dentinger, Feng Lin, Suhyun Park, Douglas Wildes, Kai Thomenius, Peter Chen, Tho Nguyen, Alan Delarama, Jong Seob Jeong, Aman Mahajan, Kalyanam Shivkumar, Omer Oralkan, David Sahn, Pierre Khuri-Yakub, Matthew O'Donnell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

A method to monitor ablative therapy by examining slope changes in the thermal strain curve caused by speed of sound with temperature is introduced. The variation of sound speed with temperature rise for most soft tissue follows a similar pattern to that of water. Unlike most liquids, the sound speed of tissue increases with temperature. However, at temperatures above about 50 °C, there is no further increase in the sound speed and the temperature coefficient may become slightly negative. For ablation therapy, an irreversible injury to tissue and a complete heart block occurs in the range of 48-50 °C for a short period in accordance with the well known Arrhenius equation. Using these two properties, we propose a potential tool to detect the moment when tissue damage occurs using the reduced slope in the thermal strain curve as a function of heating time. Using a prototype intracardiac echocardiography (ICE) array for imaging and a catheter for RF ablation, we were able to observe an obvious slope change in the thermal strain curve in an excised tissue sample. The method was further tested in-vivo, using a specially equipped ablation tip and an 11 MHz microlinear (ML) ICE array mounted on the tip of a catheter. As with in-vitro experiments, the thermal strain curve showed a plateau and a change in the sign of the slope.

Original languageEnglish (US)
Title of host publicationProceedings - IEEE Ultrasonics Symposium
Pages1364-1367
Number of pages4
DOIs
StatePublished - 2010
Event2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States
Duration: Oct 11 2010Oct 14 2010

Other

Other2010 IEEE International Ultrasonics Symposium, IUS 2010
CountryUnited States
CitySan Diego, CA
Period10/11/1010/14/10

Fingerprint

ablation
slopes
echocardiography
acoustics
curves
therapy
temperature
plateaus
prototypes
damage
moments
heating
coefficients
liquids
water

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Seo, C. H., Stephens, D., Cannata, J., Dentinger, A., Lin, F., Park, S., ... O'Donnell, M. (2010). Monitoring radiofrequency catheter ablation using thermal strain imaging. In Proceedings - IEEE Ultrasonics Symposium (pp. 1364-1367). [5935567] https://doi.org/10.1109/ULTSYM.2010.5935567

Monitoring radiofrequency catheter ablation using thermal strain imaging. / Seo, Chi Hyung; Stephens, Douglas; Cannata, Jonathan; Dentinger, Aaron; Lin, Feng; Park, Suhyun; Wildes, Douglas; Thomenius, Kai; Chen, Peter; Nguyen, Tho; Delarama, Alan; Jeong, Jong Seob; Mahajan, Aman; Shivkumar, Kalyanam; Oralkan, Omer; Sahn, David; Khuri-Yakub, Pierre; O'Donnell, Matthew.

Proceedings - IEEE Ultrasonics Symposium. 2010. p. 1364-1367 5935567.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Seo, CH, Stephens, D, Cannata, J, Dentinger, A, Lin, F, Park, S, Wildes, D, Thomenius, K, Chen, P, Nguyen, T, Delarama, A, Jeong, JS, Mahajan, A, Shivkumar, K, Oralkan, O, Sahn, D, Khuri-Yakub, P & O'Donnell, M 2010, Monitoring radiofrequency catheter ablation using thermal strain imaging. in Proceedings - IEEE Ultrasonics Symposium., 5935567, pp. 1364-1367, 2010 IEEE International Ultrasonics Symposium, IUS 2010, San Diego, CA, United States, 10/11/10. https://doi.org/10.1109/ULTSYM.2010.5935567
Seo CH, Stephens D, Cannata J, Dentinger A, Lin F, Park S et al. Monitoring radiofrequency catheter ablation using thermal strain imaging. In Proceedings - IEEE Ultrasonics Symposium. 2010. p. 1364-1367. 5935567 https://doi.org/10.1109/ULTSYM.2010.5935567
Seo, Chi Hyung ; Stephens, Douglas ; Cannata, Jonathan ; Dentinger, Aaron ; Lin, Feng ; Park, Suhyun ; Wildes, Douglas ; Thomenius, Kai ; Chen, Peter ; Nguyen, Tho ; Delarama, Alan ; Jeong, Jong Seob ; Mahajan, Aman ; Shivkumar, Kalyanam ; Oralkan, Omer ; Sahn, David ; Khuri-Yakub, Pierre ; O'Donnell, Matthew. / Monitoring radiofrequency catheter ablation using thermal strain imaging. Proceedings - IEEE Ultrasonics Symposium. 2010. pp. 1364-1367
@inproceedings{97fe2e7f3aee4097975e04fe14d697d4,
title = "Monitoring radiofrequency catheter ablation using thermal strain imaging",
abstract = "A method to monitor ablative therapy by examining slope changes in the thermal strain curve caused by speed of sound with temperature is introduced. The variation of sound speed with temperature rise for most soft tissue follows a similar pattern to that of water. Unlike most liquids, the sound speed of tissue increases with temperature. However, at temperatures above about 50 °C, there is no further increase in the sound speed and the temperature coefficient may become slightly negative. For ablation therapy, an irreversible injury to tissue and a complete heart block occurs in the range of 48-50 °C for a short period in accordance with the well known Arrhenius equation. Using these two properties, we propose a potential tool to detect the moment when tissue damage occurs using the reduced slope in the thermal strain curve as a function of heating time. Using a prototype intracardiac echocardiography (ICE) array for imaging and a catheter for RF ablation, we were able to observe an obvious slope change in the thermal strain curve in an excised tissue sample. The method was further tested in-vivo, using a specially equipped ablation tip and an 11 MHz microlinear (ML) ICE array mounted on the tip of a catheter. As with in-vitro experiments, the thermal strain curve showed a plateau and a change in the sign of the slope.",
author = "Seo, {Chi Hyung} and Douglas Stephens and Jonathan Cannata and Aaron Dentinger and Feng Lin and Suhyun Park and Douglas Wildes and Kai Thomenius and Peter Chen and Tho Nguyen and Alan Delarama and Jeong, {Jong Seob} and Aman Mahajan and Kalyanam Shivkumar and Omer Oralkan and David Sahn and Pierre Khuri-Yakub and Matthew O'Donnell",
year = "2010",
doi = "10.1109/ULTSYM.2010.5935567",
language = "English (US)",
isbn = "9781457703829",
pages = "1364--1367",
booktitle = "Proceedings - IEEE Ultrasonics Symposium",

}

TY - GEN

T1 - Monitoring radiofrequency catheter ablation using thermal strain imaging

AU - Seo, Chi Hyung

AU - Stephens, Douglas

AU - Cannata, Jonathan

AU - Dentinger, Aaron

AU - Lin, Feng

AU - Park, Suhyun

AU - Wildes, Douglas

AU - Thomenius, Kai

AU - Chen, Peter

AU - Nguyen, Tho

AU - Delarama, Alan

AU - Jeong, Jong Seob

AU - Mahajan, Aman

AU - Shivkumar, Kalyanam

AU - Oralkan, Omer

AU - Sahn, David

AU - Khuri-Yakub, Pierre

AU - O'Donnell, Matthew

PY - 2010

Y1 - 2010

N2 - A method to monitor ablative therapy by examining slope changes in the thermal strain curve caused by speed of sound with temperature is introduced. The variation of sound speed with temperature rise for most soft tissue follows a similar pattern to that of water. Unlike most liquids, the sound speed of tissue increases with temperature. However, at temperatures above about 50 °C, there is no further increase in the sound speed and the temperature coefficient may become slightly negative. For ablation therapy, an irreversible injury to tissue and a complete heart block occurs in the range of 48-50 °C for a short period in accordance with the well known Arrhenius equation. Using these two properties, we propose a potential tool to detect the moment when tissue damage occurs using the reduced slope in the thermal strain curve as a function of heating time. Using a prototype intracardiac echocardiography (ICE) array for imaging and a catheter for RF ablation, we were able to observe an obvious slope change in the thermal strain curve in an excised tissue sample. The method was further tested in-vivo, using a specially equipped ablation tip and an 11 MHz microlinear (ML) ICE array mounted on the tip of a catheter. As with in-vitro experiments, the thermal strain curve showed a plateau and a change in the sign of the slope.

AB - A method to monitor ablative therapy by examining slope changes in the thermal strain curve caused by speed of sound with temperature is introduced. The variation of sound speed with temperature rise for most soft tissue follows a similar pattern to that of water. Unlike most liquids, the sound speed of tissue increases with temperature. However, at temperatures above about 50 °C, there is no further increase in the sound speed and the temperature coefficient may become slightly negative. For ablation therapy, an irreversible injury to tissue and a complete heart block occurs in the range of 48-50 °C for a short period in accordance with the well known Arrhenius equation. Using these two properties, we propose a potential tool to detect the moment when tissue damage occurs using the reduced slope in the thermal strain curve as a function of heating time. Using a prototype intracardiac echocardiography (ICE) array for imaging and a catheter for RF ablation, we were able to observe an obvious slope change in the thermal strain curve in an excised tissue sample. The method was further tested in-vivo, using a specially equipped ablation tip and an 11 MHz microlinear (ML) ICE array mounted on the tip of a catheter. As with in-vitro experiments, the thermal strain curve showed a plateau and a change in the sign of the slope.

UR - http://www.scopus.com/inward/record.url?scp=80054767049&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80054767049&partnerID=8YFLogxK

U2 - 10.1109/ULTSYM.2010.5935567

DO - 10.1109/ULTSYM.2010.5935567

M3 - Conference contribution

SN - 9781457703829

SP - 1364

EP - 1367

BT - Proceedings - IEEE Ultrasonics Symposium

ER -