Molecular imaging with contrast enhanced ultrasound

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    Noninvasive cardiovascular imaging techniques are well-established for studying cardiovascular anatomy and physiology. Over the past decade contrast enhanced imaging techniques have been developed that are also able to characterize the molecular constituents of cardiovascular disease. In this regard, microbubble-and ultrasound-based techniques have the ability to assess a broad range of molecular components of cardiovascular pathology such as inflammation, recent ischemia, atherosclerosis, acute transplant rejection, angiogenesis, and thrombosis. The advantages of ultrasound-and microbubble-based approach include the ability to assess multiple molecular disease markers without exposure to ionizing radiation or prolonged imaging protocols. This review highlights the development of microbubble-based molecular imaging, describes successful experimental conditions in which they have been studied, and postulates the importance of translating this technique into the clinical practice.

    Original languageEnglish (US)
    Pages (from-to)667-677
    Number of pages11
    JournalJournal of Nuclear Cardiology
    Volume17
    Issue number4
    DOIs
    StatePublished - Aug 2010

    Fingerprint

    Microbubbles
    Molecular Imaging
    Cardiovascular Physiological Phenomena
    Graft Rejection
    Ionizing Radiation
    Anatomy
    Atherosclerosis
    Thrombosis
    Cardiovascular Diseases
    Ischemia
    Pathology
    Inflammation

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine
    • Radiology Nuclear Medicine and imaging

    Cite this

    Molecular imaging with contrast enhanced ultrasound. / Chadderdon, Scott; Kaul, Sanjiv.

    In: Journal of Nuclear Cardiology, Vol. 17, No. 4, 08.2010, p. 667-677.

    Research output: Contribution to journalArticle

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