Molecular imaging of cardiac amyloidosis

Ahmad Masri, Syed Bukhari, Yvonne S. Eisele, Prem Soman

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Transthyretin and light-chain amyloidosis are the 2 main causes of cardiac amyloidosis. Recent developments in molecular imaging have transformed our ability to diagnose transthyretin cardiac amyloidosis noninvasively and unmasked a hitherto unrecognized prevalence of the disease. This review summarizes the current and evolving imaging approaches, their molecular structural basis, and the gaps in imaging capabilities that have arisen as a result of parallel developments in pharmacotherapy delivering the first effective treatment options for this condition.

Original languageEnglish (US)
Pages (from-to)965-970
Number of pages6
JournalJournal of Nuclear Medicine
Volume61
Issue number7
DOIs
StatePublished - Jul 1 2020

Keywords

  • ATTR
  • Bone-seeking tracers
  • Cardiac amyloidosis
  • Molecular imaging
  • SPECT

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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