Molecular cytogenetics of human breast cancer

Joe Gray, C. Collins, I. C. Henderson, J. Isola, A. Kallioniemi, O. P. Kallioniemi, H. Nakamura, D. Pinkel, T. Stokke, M. Tanner, F. Waldman

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Our studies of human breast cancer using CGH and FISH with precisely mapped probes have revealed a surprising amount of intratumor and intertumor heterogeneity in human breast cancers. However, some regions of abnormal copy number are found frequently. We believe that the regions of frequent abnormality harbor novel cancer genes, and that identification of these is important for diagnosis, prognostication, and the development of new therapies.

Original languageEnglish (US)
Pages (from-to)645-652
Number of pages8
JournalCold Spring Harbor Symposia on Quantitative Biology
Volume59
StatePublished - 1994
Externally publishedYes

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Ports and harbors
cytogenetics
Cytogenetics
breast neoplasms
Genes
Breast Neoplasms
Neoplasm Genes
therapeutics
neoplasms
genes
Therapeutics

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Molecular Biology

Cite this

Gray, J., Collins, C., Henderson, I. C., Isola, J., Kallioniemi, A., Kallioniemi, O. P., ... Waldman, F. (1994). Molecular cytogenetics of human breast cancer. Cold Spring Harbor Symposia on Quantitative Biology, 59, 645-652.

Molecular cytogenetics of human breast cancer. / Gray, Joe; Collins, C.; Henderson, I. C.; Isola, J.; Kallioniemi, A.; Kallioniemi, O. P.; Nakamura, H.; Pinkel, D.; Stokke, T.; Tanner, M.; Waldman, F.

In: Cold Spring Harbor Symposia on Quantitative Biology, Vol. 59, 1994, p. 645-652.

Research output: Contribution to journalArticle

Gray, J, Collins, C, Henderson, IC, Isola, J, Kallioniemi, A, Kallioniemi, OP, Nakamura, H, Pinkel, D, Stokke, T, Tanner, M & Waldman, F 1994, 'Molecular cytogenetics of human breast cancer', Cold Spring Harbor Symposia on Quantitative Biology, vol. 59, pp. 645-652.
Gray J, Collins C, Henderson IC, Isola J, Kallioniemi A, Kallioniemi OP et al. Molecular cytogenetics of human breast cancer. Cold Spring Harbor Symposia on Quantitative Biology. 1994;59:645-652.
Gray, Joe ; Collins, C. ; Henderson, I. C. ; Isola, J. ; Kallioniemi, A. ; Kallioniemi, O. P. ; Nakamura, H. ; Pinkel, D. ; Stokke, T. ; Tanner, M. ; Waldman, F. / Molecular cytogenetics of human breast cancer. In: Cold Spring Harbor Symposia on Quantitative Biology. 1994 ; Vol. 59. pp. 645-652.
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