Abstract
This review describes molecular cytogenetic techniques for detection and characterization of genetic aberrations associated with human disease. The techniques of fluorescence in situ hybridization, primed in situ labeling and comparative genome hybridization are described, as are probes for repeated sequences, whole chromosomes and specific loci. Also reviewed are applications of these technologies to pre-and neonatal diagnosis and to the characterization of human malignancies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 623-631 |
| Number of pages | 9 |
| Journal | Current Opinion in Biotechnology |
| Volume | 3 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1992 |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomedical Engineering
Fingerprint Dive into the research topics of 'Molecular cytogenetics: Diagnosis and prognostic assessment'. Together they form a unique fingerprint.
Cite this
Gray, J. W., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F., & Pinkel, D. (1992). Molecular cytogenetics: Diagnosis and prognostic assessment. Current Opinion in Biotechnology, 3(6), 623-631. https://doi.org/10.1016/0958-1669(92)90006-5