Molecular cytogenetics: Diagnosis and prognostic assessment

Joe W. Gray; Anne Kallioniemi; Olli Kallioniemi; Maria Pallavicini; Fred Waldman; Daniel Pinkel

doi:10.1016/0958-1669(92)90006-5

Molecular cytogenetics: Diagnosis and prognostic assessment

Joe W. Gray, Anne Kallioniemi, Olli Kallioniemi, Maria Pallavicini, Fred Waldman, Daniel Pinkel

Biomedical Engineering

Research output: Contribution to journal › Article

21 Scopus citations

Abstract

This review describes molecular cytogenetic techniques for detection and characterization of genetic aberrations associated with human disease. The techniques of fluorescence in situ hybridization, primed in situ labeling and comparative genome hybridization are described, as are probes for repeated sequences, whole chromosomes and specific loci. Also reviewed are applications of these technologies to pre-and neonatal diagnosis and to the characterization of human malignancies.

Original language	English (US)
Pages (from-to)	623-631
Number of pages	9
Journal	Current Opinion in Biotechnology
Volume	3
Issue number	6
DOIs	https://doi.org/10.1016/0958-1669(92)90006-5
State	Published - Dec 1992

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ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

Cite this

Gray, J. W., Kallioniemi, A., Kallioniemi, O., Pallavicini, M., Waldman, F., & Pinkel, D. (1992). Molecular cytogenetics: Diagnosis and prognostic assessment. Current Opinion in Biotechnology, 3(6), 623-631. https://doi.org/10.1016/0958-1669(92)90006-5

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Access to Document

10.1016/0958-1669(92)90006-5