Langer et al. use three-dimensional bioprinting to incorporate multiple cell types, including patient-derived cells, into scaffold-free in vitro tumor tissues. They show that cells within these tissues self-organize, secrete extracellular matrix factors, and respond to extrinsic signals and that multiple tumorigenic phenotypes can be assessed simultaneously.
- 3D tumor models
- breast cancer
- pancreatic cancer
- three-dimensional bioprinting
- tumor microenvironment
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)