Investigation of the mechanisms underlying scaffold degradation and neotissue synthesis is essential to understanding the mechanical and biological performance of engineered tissues. Modeling the dynamic composition of cell-polymer constructs may be useful in estimating the constructs' long-term function. In this preliminary study, we identified potential mechanisms and developed mathematical models to describe scaffold mass loss and extracellular matrix synthesis for engineered cartilage.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Society of Mechanical Engineers, Bioengineering Division (Publication) BED|
|State||Published - 2001|
|Event||2001 ASME International Mechanical Engineering Congress and Exposition - New York, NY, United States|
Duration: Nov 11 2001 → Nov 16 2001
ASJC Scopus subject areas