TY - JOUR
T1 - Modeling the dynamic composition of engineered cartilage
AU - Wilson, Christopher G.
AU - Kohles, Sean S.
AU - Bonassar, Lawrence J.
N1 - Funding Information:
The authors recognize the technical contributions of Dr. Amit Roy, Dr. Jill Rulfs, Nicholas Genes, Nichole Mercier, Morgan Hott, Brett Downing, and Dr. George Pins. Funding for this project was provided by the Center for Tissue Engineering, University of Massachusetts Medical School, the Office for Academic Affairs, Worcester Polytechnic Institute, and Grant DE014288 from the National Institute for Dental and Craniofacial Research.
PY - 2001
Y1 - 2001
N2 - Investigation of the mechanisms underlying scaffold degradation and neotissue synthesis is essential to understanding the mechanical and biological performance of engineered tissues. Modeling the dynamic composition of cell-polymer constructs may be useful in estimating the constructs' long-term function. In this preliminary study, we identified potential mechanisms and developed mathematical models to describe scaffold mass loss and extracellular matrix synthesis for engineered cartilage.
AB - Investigation of the mechanisms underlying scaffold degradation and neotissue synthesis is essential to understanding the mechanical and biological performance of engineered tissues. Modeling the dynamic composition of cell-polymer constructs may be useful in estimating the constructs' long-term function. In this preliminary study, we identified potential mechanisms and developed mathematical models to describe scaffold mass loss and extracellular matrix synthesis for engineered cartilage.
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UR - http://www.scopus.com/inward/citedby.url?scp=0242721892&partnerID=8YFLogxK
M3 - Conference article
AN - SCOPUS:0242721892
SN - 1071-6947
VL - 51
SP - 15
EP - 16
JO - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
JF - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
T2 - 2001 ASME International Mechanical Engineering Congress and Exposition
Y2 - 11 November 2001 through 16 November 2001
ER -