Modeling photon transport in transabdominal fetal oximetry

Steven Jacques, Nimmi Ramanujam, Gargi Vishnoi, Regine Choe, Britton Chance

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The possibility of optical oximetry of the blood in the fetal brain measured across the maternal abdomen just prior to birth is under investigation. Such measurements could detect fetal distress prior to birth and aid in the clinical decision regarding Cesarean section. This paper uses a perturbation method to model photon transport through an 8-cm-diam fetal brain located at a constant 2.5 cm below a curved maternal abdominal surface with an air/tissue boundary. In the simulation, a near-infrared light source delivers light to the abdomen and a detector is positioned up to 10 cm from the source along the arc of the abdominal surface. The light transport [W/cm2 fluence rate per W incident power] collected at the 10 cm position is Tm = 2.2×10-6 cm-2 if the fetal brain has the same optical properties as the mother and Tf = 1.0×10-6 cm-2 for an optically perturbing fetal brain with typical brain optical properties. The perturbation P = (Tf-Tm)/Tm is -53% due to the fetal brain. The model illustrates the challenge and feasibility of transabdominal oximetry of the fetal brain.

Original languageEnglish (US)
Pages (from-to)277-282
Number of pages6
JournalJournal of Biomedical Optics
Volume5
Issue number3
DOIs
StatePublished - Jul 2000

Fingerprint

oximetry
Oximetry
Photons
brain
Brain
photons
abdomen
Light
Abdomen
Optical properties
Mothers
Parturition
optical properties
perturbation
Fetal Distress
Fetal Blood
Cesarean Section
blood
Light sources
light sources

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Atomic and Molecular Physics, and Optics
  • Radiological and Ultrasound Technology

Cite this

Jacques, S., Ramanujam, N., Vishnoi, G., Choe, R., & Chance, B. (2000). Modeling photon transport in transabdominal fetal oximetry. Journal of Biomedical Optics, 5(3), 277-282. https://doi.org/10.1117/1.429996

Modeling photon transport in transabdominal fetal oximetry. / Jacques, Steven; Ramanujam, Nimmi; Vishnoi, Gargi; Choe, Regine; Chance, Britton.

In: Journal of Biomedical Optics, Vol. 5, No. 3, 07.2000, p. 277-282.

Research output: Contribution to journalArticle

Jacques, S, Ramanujam, N, Vishnoi, G, Choe, R & Chance, B 2000, 'Modeling photon transport in transabdominal fetal oximetry', Journal of Biomedical Optics, vol. 5, no. 3, pp. 277-282. https://doi.org/10.1117/1.429996
Jacques S, Ramanujam N, Vishnoi G, Choe R, Chance B. Modeling photon transport in transabdominal fetal oximetry. Journal of Biomedical Optics. 2000 Jul;5(3):277-282. https://doi.org/10.1117/1.429996
Jacques, Steven ; Ramanujam, Nimmi ; Vishnoi, Gargi ; Choe, Regine ; Chance, Britton. / Modeling photon transport in transabdominal fetal oximetry. In: Journal of Biomedical Optics. 2000 ; Vol. 5, No. 3. pp. 277-282.
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