Minimally invasive LVAD deactivation in a 65-year-old man with recurrent pump thrombosis and left ventricular recovery

Akshay Pendyal, Christopher Chien, James Mudd, Jill Gelow

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Pump thrombosis is a dire sequela after left ventricular assist device (LVAD) implantation. Treatment comprises antiplatelet agents, anticoagulants, thrombolytic agents, and pump exchange. Although pump exchange is the definitive therapy, it is also the most invasive, often exposing patients to the risks of repeat sternotomy and cardiopulmonary bypass. In some cases, patients experience left ventricular recovery after LVAD implantation. The optimal strategy surrounding the management of LVADs in patients who have experienced ventricular recovery is unknown; techniques range from total system explantation to partial pump resection. Here, we describe a novel means of LVAD deactivation in a 65-year-old man with recurrent pump thrombosis, via percutaneous outflow graft closure in the cardiac catheterization laboratory. We also review the existing literature on surgical and percu taneous LVAD deactivation techniques.

Original languageEnglish (US)
Pages (from-to)70-72
Number of pages3
JournalTexas Heart Institute Journal
Volume44
Issue number1
DOIs
StatePublished - Feb 1 2017

Fingerprint

Heart-Assist Devices
Thrombosis
Sternotomy
Fibrinolytic Agents
Platelet Aggregation Inhibitors
Cardiac Catheterization
Cardiopulmonary Bypass
Anticoagulants
Transplants
Therapeutics

Keywords

  • Device removal/instrumentation/methods
  • Heart failure/rehabilitation
  • Heart-assist devices/adverse effects
  • Recovery of function/physiology
  • Thrombosis/etiology
  • Treatment outcome
  • Ventricular function/physiology

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Minimally invasive LVAD deactivation in a 65-year-old man with recurrent pump thrombosis and left ventricular recovery. / Pendyal, Akshay; Chien, Christopher; Mudd, James; Gelow, Jill.

In: Texas Heart Institute Journal, Vol. 44, No. 1, 01.02.2017, p. 70-72.

Research output: Contribution to journalReview article

@article{e6ad29335e484d20a8bd5a46579997c1,
title = "Minimally invasive LVAD deactivation in a 65-year-old man with recurrent pump thrombosis and left ventricular recovery",
abstract = "Pump thrombosis is a dire sequela after left ventricular assist device (LVAD) implantation. Treatment comprises antiplatelet agents, anticoagulants, thrombolytic agents, and pump exchange. Although pump exchange is the definitive therapy, it is also the most invasive, often exposing patients to the risks of repeat sternotomy and cardiopulmonary bypass. In some cases, patients experience left ventricular recovery after LVAD implantation. The optimal strategy surrounding the management of LVADs in patients who have experienced ventricular recovery is unknown; techniques range from total system explantation to partial pump resection. Here, we describe a novel means of LVAD deactivation in a 65-year-old man with recurrent pump thrombosis, via percutaneous outflow graft closure in the cardiac catheterization laboratory. We also review the existing literature on surgical and percu taneous LVAD deactivation techniques.",
keywords = "Device removal/instrumentation/methods, Heart failure/rehabilitation, Heart-assist devices/adverse effects, Recovery of function/physiology, Thrombosis/etiology, Treatment outcome, Ventricular function/physiology",
author = "Akshay Pendyal and Christopher Chien and James Mudd and Jill Gelow",
year = "2017",
month = "2",
day = "1",
doi = "10.14503/THIJ-16-5787",
language = "English (US)",
volume = "44",
pages = "70--72",
journal = "Texas Heart Institute Journal",
issn = "0730-2347",
publisher = "Texas Heart Institute",
number = "1",

}

TY - JOUR

T1 - Minimally invasive LVAD deactivation in a 65-year-old man with recurrent pump thrombosis and left ventricular recovery

AU - Pendyal, Akshay

AU - Chien, Christopher

AU - Mudd, James

AU - Gelow, Jill

PY - 2017/2/1

Y1 - 2017/2/1

N2 - Pump thrombosis is a dire sequela after left ventricular assist device (LVAD) implantation. Treatment comprises antiplatelet agents, anticoagulants, thrombolytic agents, and pump exchange. Although pump exchange is the definitive therapy, it is also the most invasive, often exposing patients to the risks of repeat sternotomy and cardiopulmonary bypass. In some cases, patients experience left ventricular recovery after LVAD implantation. The optimal strategy surrounding the management of LVADs in patients who have experienced ventricular recovery is unknown; techniques range from total system explantation to partial pump resection. Here, we describe a novel means of LVAD deactivation in a 65-year-old man with recurrent pump thrombosis, via percutaneous outflow graft closure in the cardiac catheterization laboratory. We also review the existing literature on surgical and percu taneous LVAD deactivation techniques.

AB - Pump thrombosis is a dire sequela after left ventricular assist device (LVAD) implantation. Treatment comprises antiplatelet agents, anticoagulants, thrombolytic agents, and pump exchange. Although pump exchange is the definitive therapy, it is also the most invasive, often exposing patients to the risks of repeat sternotomy and cardiopulmonary bypass. In some cases, patients experience left ventricular recovery after LVAD implantation. The optimal strategy surrounding the management of LVADs in patients who have experienced ventricular recovery is unknown; techniques range from total system explantation to partial pump resection. Here, we describe a novel means of LVAD deactivation in a 65-year-old man with recurrent pump thrombosis, via percutaneous outflow graft closure in the cardiac catheterization laboratory. We also review the existing literature on surgical and percu taneous LVAD deactivation techniques.

KW - Device removal/instrumentation/methods

KW - Heart failure/rehabilitation

KW - Heart-assist devices/adverse effects

KW - Recovery of function/physiology

KW - Thrombosis/etiology

KW - Treatment outcome

KW - Ventricular function/physiology

UR - http://www.scopus.com/inward/record.url?scp=85013372256&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85013372256&partnerID=8YFLogxK

U2 - 10.14503/THIJ-16-5787

DO - 10.14503/THIJ-16-5787

M3 - Review article

VL - 44

SP - 70

EP - 72

JO - Texas Heart Institute Journal

JF - Texas Heart Institute Journal

SN - 0730-2347

IS - 1

ER -