Mie and Rayleigh modeling of visible-light scattering in neonatal skin

Iyad S. Saidi, Steven Jacques, Frank K. Tittel

Research output: Contribution to journalArticle

210 Citations (Scopus)

Abstract

Reduced-scattering coefficients of neonatal skin were deduced in the 450-750-nm range from integratingsphere measurements of the total reflection and total transmission of 22 skin samples. The reducedscattering coefficients increased linearly at each wavelength with gestational maturity. The distribution of diameters d and concentration ρA of the skin-sample collagen fibers were measured in histological sections of nine neonatal skin samples of varying gestational ages. An algorithm that calculates Mie scattering by cylinders was used to model the scattering by the collagen fibers in the skin. The fraction of the reduced-scattering coefficient μs′ that was attributable to Mie scattering by collagen fibers, as deduced from wavelength-dependent analysis, increased with gestational age and approached that found for adult skin. An assignment of 1.017 for nrel, the refractive index of the collagen fibers relative to that of the surrounding medium, allowed the values for Mie scattering by collagen fibers, as predicted by the model for each of the nine neonatal skin samples to match the values for Mie scattering by collagen fibers as expected from the measurements of μs′. The Mie-scattering model predicted an increase in scattering with gestational age on the basis of changes in the collagen-fiber diameters, and this increase was proportional to that measured with the integrating-sphere method.

Original languageEnglish (US)
Pages (from-to)7410-7418
Number of pages9
JournalApplied Optics
Volume34
Issue number31
DOIs
StatePublished - Nov 1 1995
Externally publishedYes

Fingerprint

collagens
Light scattering
Skin
light scattering
Mie scattering
Collagen
Scattering
fibers
Fibers
scattering coefficients
scattering
Wavelength
wavelengths
refractivity
Refractive index
coefficients

Keywords

  • Mie
  • Neonatal skin
  • Optical properties
  • Rayleigh
  • Scattering

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Mie and Rayleigh modeling of visible-light scattering in neonatal skin. / Saidi, Iyad S.; Jacques, Steven; Tittel, Frank K.

In: Applied Optics, Vol. 34, No. 31, 01.11.1995, p. 7410-7418.

Research output: Contribution to journalArticle

Saidi, Iyad S. ; Jacques, Steven ; Tittel, Frank K. / Mie and Rayleigh modeling of visible-light scattering in neonatal skin. In: Applied Optics. 1995 ; Vol. 34, No. 31. pp. 7410-7418.
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