Abstract
Interfacing a novel micron-resolution particle image velocimetry and dual optical tweezers system (μPIVOT) with microfluidics facilitates the exposure of an individual biologic cell to a wide range of static and dynamic mechanical stress conditions. Single cells can be manipulated in a sequence of mechanical stresses (hydrostatic pressure variations, tension or compression, as well as shear and extensional fluid induced stresses) while measuring cellular deformation. The unique multimodal load states enable a new realm of single cell biomechanical studies.
| Original language | English (US) |
|---|---|
| Title of host publication | ASME International Mechanical Engineering Congress and Exposition, Proceedings |
| Pages | 839-841 |
| Number of pages | 3 |
| Volume | 11 PART B |
| DOIs | |
| State | Published - 2008 |
| Event | ASME International Mechanical Engineering Congress and Exposition, IMECE 2007 - Seattle, WA, United States Duration: Nov 11 2007 → Nov 15 2007 |
Other
| Other | ASME International Mechanical Engineering Congress and Exposition, IMECE 2007 |
|---|---|
| Country | United States |
| City | Seattle, WA |
| Period | 11/11/07 → 11/15/07 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Microfluidics supporting an optical instrument for multimodal single cell biomechanics. / Nève, Nathalie; Lingwood, James K.; Winn, Shelley R.; Tretheway, Derek C.; Kohles, Sean.
ASME International Mechanical Engineering Congress and Exposition, Proceedings. Vol. 11 PART B 2008. p. 839-841.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Microfluidics supporting an optical instrument for multimodal single cell biomechanics
AU - Nève, Nathalie
AU - Lingwood, James K.
AU - Winn, Shelley R.
AU - Tretheway, Derek C.
AU - Kohles, Sean
PY - 2008
Y1 - 2008
N2 - Interfacing a novel micron-resolution particle image velocimetry and dual optical tweezers system (μPIVOT) with microfluidics facilitates the exposure of an individual biologic cell to a wide range of static and dynamic mechanical stress conditions. Single cells can be manipulated in a sequence of mechanical stresses (hydrostatic pressure variations, tension or compression, as well as shear and extensional fluid induced stresses) while measuring cellular deformation. The unique multimodal load states enable a new realm of single cell biomechanical studies.
AB - Interfacing a novel micron-resolution particle image velocimetry and dual optical tweezers system (μPIVOT) with microfluidics facilitates the exposure of an individual biologic cell to a wide range of static and dynamic mechanical stress conditions. Single cells can be manipulated in a sequence of mechanical stresses (hydrostatic pressure variations, tension or compression, as well as shear and extensional fluid induced stresses) while measuring cellular deformation. The unique multimodal load states enable a new realm of single cell biomechanical studies.
UR - http://www.scopus.com/inward/record.url?scp=44349155345&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44349155345&partnerID=8YFLogxK
U2 - 10.1115/IMECE2007-42004
DO - 10.1115/IMECE2007-42004
M3 - Conference contribution
AN - SCOPUS:44349155345
SN - 079184305X
SN - 9780791843055
VL - 11 PART B
SP - 839
EP - 841
BT - ASME International Mechanical Engineering Congress and Exposition, Proceedings
ER -