Microbubbles in medical imaging: Current applications and future directions

    Research output: Contribution to journalArticle

    580 Scopus citations


    Not all bubbles in the bloodstream are detrimental. During the past decade, contrast-enhanced ultrasound has evolved from a purely investigational tool to a routine diagnostic technique. This transformation has been facilitated by advances in the microbubble contrast agents and contrast-specific ultrasound imaging techniques. The ability to non-invasively image molecular events with targeted microbubbles is likely to be important for characterizing pathophysiology and for developing new therapeutic strategies in the treatment of cardiovascular and neoplastic diseases.

    Original languageEnglish (US)
    Pages (from-to)527-532
    Number of pages6
    JournalNature Reviews Drug Discovery
    Issue number6
    StatePublished - Jun 2004

    ASJC Scopus subject areas

    • Pharmacology
    • Drug Discovery

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