Methods for obtaining and analyzing unattended polysomnography data for a multicenter study

Susan Redline, Mark H. Sanders, Bonnie K. Lind, Stuart F. Quan, Conrad Iber, Daniel J. Gottlieb, William H. Bonekat, David M. Rapoport, Philip L. Smith, James P. Kiley

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Abstract

This paper reviews the data collection, processing, and analysis approaches developed to obtain comprehensive unattended polysomnographic data for the Sleep Heart Health Study, a multicenter study of the cardiovascular consequences of sleep-disordered breathing. Protocols were developed and implemented to standardize in-home data collection procedures and to perform centralized sleep scoring. Of 7027 studies performed on 6697 participants, 5 534 studies were determined to be technically acceptable (failure rate 5.3%). Quality grades varied over time, reflecting the influences of variable technician experience, and equipment aging and modifications. Eighty-seven percent of studies were judged to be of 'good' quality or better, and 75% were judged to be of sufficient quality to provide reliable sleep staging and arousal data. Poor submental EMG (electromyogram) accounted for the largest proportion of poor signal grades (9% of studies had <2 hours artifact free EMG signal). These data suggest that with rigorous training and clear protocols for data collection and processing, good-quality multichannel polysomnography data can be obtained for a majority of unattended studies performed in a research setting. Data most susceptible to poor signal quality are sleep staging and arousal data that require clear EEG (electroencephalograph) and EMG signals.

Original languageEnglish (US)
Pages (from-to)759-767
Number of pages9
JournalSleep
Volume21
Issue number7
StatePublished - Nov 1 1998

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Keywords

  • Epidemiology
  • Polysomnography
  • Sleep apnea

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)

Cite this

Redline, S., Sanders, M. H., Lind, B. K., Quan, S. F., Iber, C., Gottlieb, D. J., Bonekat, W. H., Rapoport, D. M., Smith, P. L., & Kiley, J. P. (1998). Methods for obtaining and analyzing unattended polysomnography data for a multicenter study. Sleep, 21(7), 759-767.