Objectives: Review the literature on methicillin-resistant Staphylococcus aureus (MRSA) infection following septorhinoplasty, identify patient groups at risk for MRSA complications following septorhinoplasty, and evaluate the need for antibiotic prophylaxis in these patients. Discussion: Patients who are susceptible to MRSA infections may also be at higher risk for nasal colonization, and this includes elderly patients, patients recently hospitalized or treated in a rehabilitation center, and healthcare workers. Few cases of MRSA infection following septorhinoplasty have been reported in the literature. Prevention of nosocomial and postsurgical MRSA infections has been well studied, and it seems that elimination of nasal colonization is a major step in preventing these infections. Conclusions: Patients at increased risk for MRSA colonization should be screened prior to septorhinoplasty and if positive treated with antibiotic prophylaxis consisting of elimination of nasal carriage prior to surgery. Perioperative systemic antibiotic use should be considered, especially in revision cases.
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