Methicillin-Resistant Staphylococcus aureus in Patients With Congenital Heart Disease in the Pediatric Intensive Care Unit

Saran Wells, Tiffany Anderson, Alexander Tiemieier, Joanna Wrobel, Nizar Maraqa, Carmen Smotherman, Sarah Wheeler, Christine Bailey, Dale Kraemer, Mobeen H. Rathore

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) colonization has been recognized as a significant problem among hospitalized patients. Available data about prevalence of MRSA among children with congenital heart disease (CHD) are minimal. The aim of the study was to determine the prevalence of MRSA colonization and to identify risk factors for MRSA colonization among children <19 years old with CHD admitted to a pediatric intensive care unit (PICU). Admission and weekly MRSA nasal surveillance testing was performed, and patients were stratified into six risk groups based on the Risk Adjustment for Congenital Heart Surgery-1 Method. The MRSA-colonized children were compared to the MRSA noncolonized children. During the 3-year study period, there were 372 admissions of children with CHD to the PICU. Of the 372, 72 (19.4%) had no surveillance cultures performed or had no prior history of MRSA and were excluded from further analysis. Of the remaining 300 admissions, 29 (9.7%) (263 individual children) were found to be colonized. The mean age of the 263 children when first admitted to the PICU was 3.29 years (range 0.03-18.30, median 0.66). Age distribution was not significantly different between the colonized and noncolonized groups (P = .236). Gender (P = .667), race (P = .837), and CHD complexity (P = .395) were not significantly associated with colonization. The odds of being colonized if previously hospitalized were 4.42 times greater than if not previously hospitalized (95% confidence interval 1.89, 10.34). Routine MRSA surveillance should be performed in patients with CHD to identify colonized patients.

Original languageEnglish (US)
Pages (from-to)344-348
Number of pages5
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Volume4
Issue number4
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

Fingerprint

Pediatric Intensive Care Units
Methicillin-Resistant Staphylococcus aureus
Heart Diseases
Risk Adjustment
Age Distribution
Nose
Thoracic Surgery
Confidence Intervals

Keywords

  • congenital heart disease
  • MRSA colonization
  • surveillance cultures

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

Cite this

Methicillin-Resistant Staphylococcus aureus in Patients With Congenital Heart Disease in the Pediatric Intensive Care Unit. / Wells, Saran; Anderson, Tiffany; Tiemieier, Alexander; Wrobel, Joanna; Maraqa, Nizar; Smotherman, Carmen; Wheeler, Sarah; Bailey, Christine; Kraemer, Dale; Rathore, Mobeen H.

In: World Journal for Pediatric and Congenital Heart Surgery, Vol. 4, No. 4, 01.01.2013, p. 344-348.

Research output: Contribution to journalArticle

Wells, Saran ; Anderson, Tiffany ; Tiemieier, Alexander ; Wrobel, Joanna ; Maraqa, Nizar ; Smotherman, Carmen ; Wheeler, Sarah ; Bailey, Christine ; Kraemer, Dale ; Rathore, Mobeen H. / Methicillin-Resistant Staphylococcus aureus in Patients With Congenital Heart Disease in the Pediatric Intensive Care Unit. In: World Journal for Pediatric and Congenital Heart Surgery. 2013 ; Vol. 4, No. 4. pp. 344-348.
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