Methemoglobinemia as a complication of 20% benzocaine spray for endoscopy

Judith F. Collins

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Topical 20% benzocaine (Hurricaine, Beutlich, Inc., Niles, Ill.) spray is frequently used for oral anesthesia before upper endoscopy. Side effects attributed to this agent are exceedingly rare. The author reports one of these rare complications, drug-induced methemoglobinemia, in a patient with methemoglobin reductase deficiency. The mechanisms for the development of methemoglobinemia and its treatment are reviewed.

Original languageEnglish (US)
Pages (from-to)211-213
Number of pages3
Issue number1
StatePublished - Jan 1990

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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