Methamphetamine-induced insulin release

Edward M. Mcmahon, Dana Andersen, Jerome M. Feldman, Saul M. Schanberg

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Administration of methamphetamine or amphetamine to rats and mice produces a rapid increase in the level of immunoassayable plasma insulin not attributable to hyperglycemia. While in the mouse this release of insulin is followed consistently by a profound hypoglycemia, in the rat this response is variable. Studies in vitro demonstrate that insulin is released by a direct effect of methamphetamine on the pancreas.

Original languageEnglish (US)
Pages (from-to)66-68
Number of pages3
JournalScience
Volume174
Issue number4004
StatePublished - 1971
Externally publishedYes

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Methamphetamine
Insulin
Amphetamine
Hypoglycemia
Hyperglycemia
Pancreas

ASJC Scopus subject areas

  • General

Cite this

Mcmahon, E. M., Andersen, D., Feldman, J. M., & Schanberg, S. M. (1971). Methamphetamine-induced insulin release. Science, 174(4004), 66-68.

Methamphetamine-induced insulin release. / Mcmahon, Edward M.; Andersen, Dana; Feldman, Jerome M.; Schanberg, Saul M.

In: Science, Vol. 174, No. 4004, 1971, p. 66-68.

Research output: Contribution to journalArticle

Mcmahon, EM, Andersen, D, Feldman, JM & Schanberg, SM 1971, 'Methamphetamine-induced insulin release', Science, vol. 174, no. 4004, pp. 66-68.
Mcmahon EM, Andersen D, Feldman JM, Schanberg SM. Methamphetamine-induced insulin release. Science. 1971;174(4004):66-68.
Mcmahon, Edward M. ; Andersen, Dana ; Feldman, Jerome M. ; Schanberg, Saul M. / Methamphetamine-induced insulin release. In: Science. 1971 ; Vol. 174, No. 4004. pp. 66-68.
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