Methamphetamine-induced insulin release

Edward M. Mcmahon, Dana K. Andersen, Jerome M. Feldman, Saul M. Schanberg

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Administration of methamphetamine or amphetamine to rats and mice produces a rapid increase in the level of immunoassayable plasma insulin not attributable to hyperglycemia. While in the mouse this release of insulin is followed consistently by a profound hypoglycemia, in the rat this response is variable. Studies in vitro demonstrate that insulin is released by a direct effect of methamphetamine on the pancreas.

Original languageEnglish (US)
Pages (from-to)66-68
Number of pages3
JournalScience
Volume174
Issue number4004
DOIs
StatePublished - Jan 1 1971
Externally publishedYes

ASJC Scopus subject areas

  • General

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    Mcmahon, E. M., Andersen, D. K., Feldman, J. M., & Schanberg, S. M. (1971). Methamphetamine-induced insulin release. Science, 174(4004), 66-68. https://doi.org/10.1126/science.174.4004.66