Metachronous manifestations of Sweet's syndrome in a neutropenic patient with Fanconi anemia

Kevin Chatham-Stephens, Theresa Devere, Judith Guzman-Cottrill, Peter Kurre

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Sweet's syndrome (SS) is an acute, febrile neutrophilic dermatosis that frequently presents with leukocytosis and erythematous plaques. Lesions show neutrophilic infiltration of the dermis and rarely other organs. We report the case of an adolescent male with chronic pancytopenia secondary to Fanconi anemia (FA) who presented with acute respiratory distress. Despite an exhaustive and ultimately unrevealing work-up, the diagnosis of pulmonary SS was not made until he developed characteristic cutaneous lesions 4 months later. Comprehensive review of pathological specimens revealed metachronous SS manifestations with infiltrates in lung parenchyma, dermis, and subcutis in this neutropenic patient.

Original languageEnglish (US)
Pages (from-to)128-130
Number of pages3
JournalPediatric Blood and Cancer
Volume51
Issue number1
DOIs
StatePublished - Jul 1 2008

Keywords

  • Fanconi anemia
  • Neutropenia
  • Sweet's syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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