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Metabolism, tissue distribution, and elimination kinetics of phenytoin in the frog
S. W. Johnson
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Article
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peer-review
6
Scopus citations
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Medicine & Life Sciences
Phenytoin
84%
Tissue Distribution
80%
Anura
79%
Kinetics
53%
5-phenylhydantoin
47%
Rana pipiens
37%
5-(3,4-dihydroxyphenyl)-5-phenylhydantoin
30%
5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin
29%
Lymph
27%
trans-1,2-dihydro-1,2-naphthalenediol
19%
catechol
17%
Gastrointestinal Contents
14%
Biotransformation
14%
Bile
12%
Half-Life
10%
Mammals
10%
Pancreas
10%
Kidney
6%
Brain
6%
Chemical Compounds
Phenytoin
100%
Pharmacological Metabolism
57%
Metabolite
26%
Glucuronic Acid
15%
Catechol
12%
Reaction Half Life
11%
Rate Constant
8%
Plasma
7%