TY - JOUR
T1 - Memory Decline and Depression Onset in U.S. and European Older Adults
AU - Bendayan, Rebecca
AU - Kelly, Amanda
AU - Hofer, Scott M.
AU - Piccinin, Andrea M.
AU - Muniz-Terrera, Graciela
N1 - Funding Information:
The authors would like to acknowledge the Health and Retirement Study, which is conducted by the Institute for Social Research at the University of Michigan, with grants from the National Institute on Aging (U01AG09740) and the Social Security Administration. The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the National Institute on Aging of the National Institutes of Health under award number P01AG043362 for the Integrative Analysis of Longitudinal Studies of Aging (IALSA) research network. RB was supported in part by grant MR/R016372/1 for the King?s College London MRC Skills Development Fellowship program funded by the UK Medical Research Council (MRC) and by grant IS-BRC-1215-20018 for the National Institute for Health Research (NIHR) Biomedical Research Center at South London and Maudsley NHS Foundation Trust and King?s College London. The SHARE data collection has been primarily funded by the European Commission through FP5 (QLK6-CT-2001-00360), FP6 (SHARE-I3: RII-CT-2006-062193, COMPARE: CIT5-CT-2005-028857, SHARELIFE: CIT4-CT-2006-028812) and FP7 (SHARE-PREP: N?211909, SHARE-LEAP: N?227822, SHARE M4: N?261982). Additional funding from the German Ministry of Education and Research, the U.S. National Institute on Aging (U01_AG09740-13S2, P01_AG005842, P01_AG08291, P30_AG12815, R21_AG025169, Y1-AG-4553-01, IAG_BSR06-11, OGHA_04-064) and from various national funding sources is gratefully acknowledged (see www.share-project.org)
Publisher Copyright:
© The Author(s) 2018.
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Objectives: We explore the association between different patterns of change in depressive symptoms and memory trajectories in US and European Mediterranean (Spain, France, Italy, and Israel) and non-Mediterranean (Sweden, Denmark, Netherlands, Germany, Belgium, Switzerland, and Austria) older adults. Methods: Samples consisted of 3,466 participants from the Health Retirement Study (HRS) and 3,940 participants from the Survey of Health, Aging and Retirement (SHARE). Individuals were grouped as follows: non-case depression (NO DEP), persistent depression (DEP), depression onset (ONSET), depression recovery (RECOV), and fluctuating (FLUCT). Memory was measured using immediate and delayed recall tests. Linear mixed models were used. Results: DEP and RECOV had significantly lower baseline memory scores compared to NO DEP, at intercept level. At slope level, ONSET had a significantly faster decline in both tasks compared to NO DEP. Discussion: Cross-cohort robust and consistent new empirical evidence on the association between depression onset and faster decline in memory scores is provided.
AB - Objectives: We explore the association between different patterns of change in depressive symptoms and memory trajectories in US and European Mediterranean (Spain, France, Italy, and Israel) and non-Mediterranean (Sweden, Denmark, Netherlands, Germany, Belgium, Switzerland, and Austria) older adults. Methods: Samples consisted of 3,466 participants from the Health Retirement Study (HRS) and 3,940 participants from the Survey of Health, Aging and Retirement (SHARE). Individuals were grouped as follows: non-case depression (NO DEP), persistent depression (DEP), depression onset (ONSET), depression recovery (RECOV), and fluctuating (FLUCT). Memory was measured using immediate and delayed recall tests. Linear mixed models were used. Results: DEP and RECOV had significantly lower baseline memory scores compared to NO DEP, at intercept level. At slope level, ONSET had a significantly faster decline in both tasks compared to NO DEP. Discussion: Cross-cohort robust and consistent new empirical evidence on the association between depression onset and faster decline in memory scores is provided.
KW - HRS
KW - SHARE
KW - cognitive decline
KW - depressive symptoms
KW - replication
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U2 - 10.1177/0898264318813019
DO - 10.1177/0898264318813019
M3 - Article
C2 - 30466361
AN - SCOPUS:85059441516
VL - 32
SP - 189
EP - 198
JO - Journal of Aging and Health
JF - Journal of Aging and Health
SN - 0898-2643
IS - 3-4
ER -