Abstract
A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated "depressogenic" medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 283-292 |
| Number of pages | 10 |
| Journal | International Journal of Psychiatry in Medicine |
| Volume | 18 |
| Issue number | 3 |
| State | Published - 1988 |
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ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Medication-associated depression : a two and one-half year follow-up of a community sample. / Maricle, R. A.; Kinzie, John (Dave); Lewinsohn, P.
In: International Journal of Psychiatry in Medicine, Vol. 18, No. 3, 1988, p. 283-292.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Medication-associated depression
T2 - a two and one-half year follow-up of a community sample.
AU - Maricle, R. A.
AU - Kinzie, John (Dave)
AU - Lewinsohn, P.
PY - 1988
Y1 - 1988
N2 - A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated "depressogenic" medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.
AB - A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated "depressogenic" medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024251495&partnerID=8YFLogxK
M3 - Article
C2 - 3215717
AN - SCOPUS:0024251495
VL - 18
SP - 283
EP - 292
JO - International Journal of Psychiatry in Medicine
JF - International Journal of Psychiatry in Medicine
SN - 0091-2174
IS - 3
ER -