Medication-associated depression: a two and one-half year follow-up of a community sample.

R. A. Maricle, John (Dave) Kinzie, P. Lewinsohn

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated "depressogenic" medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.

    Original languageEnglish (US)
    Pages (from-to)283-292
    Number of pages10
    JournalInternational Journal of Psychiatry in Medicine
    Volume18
    Issue number3
    StatePublished - 1988

    Fingerprint

    Epidemiologic Studies
    Recurrence

    ASJC Scopus subject areas

    • Psychiatry and Mental health

    Cite this

    Medication-associated depression : a two and one-half year follow-up of a community sample. / Maricle, R. A.; Kinzie, John (Dave); Lewinsohn, P.

    In: International Journal of Psychiatry in Medicine, Vol. 18, No. 3, 1988, p. 283-292.

    Research output: Contribution to journalArticle

    @article{1e7e8de965ac434280eccd303a0c838b,
    title = "Medication-associated depression: a two and one-half year follow-up of a community sample.",
    abstract = "A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated {"}depressogenic{"} medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.",
    author = "Maricle, {R. A.} and Kinzie, {John (Dave)} and P. Lewinsohn",
    year = "1988",
    language = "English (US)",
    volume = "18",
    pages = "283--292",
    journal = "International Journal of Psychiatry in Medicine",
    issn = "0091-2174",
    publisher = "Baywood Publishing Co. Inc.",
    number = "3",

    }

    TY - JOUR

    T1 - Medication-associated depression

    T2 - a two and one-half year follow-up of a community sample.

    AU - Maricle, R. A.

    AU - Kinzie, John (Dave)

    AU - Lewinsohn, P.

    PY - 1988

    Y1 - 1988

    N2 - A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated "depressogenic" medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.

    AB - A community sample of forty subjects (of a total of 50) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated "depressogenic" medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.

    UR - http://www.scopus.com/inward/record.url?scp=0024251495&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0024251495&partnerID=8YFLogxK

    M3 - Article

    C2 - 3215717

    AN - SCOPUS:0024251495

    VL - 18

    SP - 283

    EP - 292

    JO - International Journal of Psychiatry in Medicine

    JF - International Journal of Psychiatry in Medicine

    SN - 0091-2174

    IS - 3

    ER -