Mechanisms of chromatin assembly and transcription

Shilpa Kadam, Beverly Emerson

Research output: Contribution to journalReview article

56 Citations (Scopus)

Abstract

Fundamental mechanisms that regulate chromatin assembly and transcription have been elucidated recently using genetics and highly defined biochemical systems. Once DNA is packaged into chromatin, its function is controlled by the ordered recruitment of diverse enzymatic complexes that structurally remodel or chemically modify nucleosomes. Recent studies provide insight into the functional selectivity of chromatin-remodeling and -modifying complexes and how they act in specific combinations to regulate individual genes and cellular pathways.

Original languageEnglish (US)
Pages (from-to)262-268
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume14
Issue number3
DOIs
StatePublished - Jun 1 2002
Externally publishedYes

Fingerprint

Chromatin Assembly and Disassembly
Nucleosomes
Chromatin
DNA
Genes

ASJC Scopus subject areas

  • Cell Biology

Cite this

Mechanisms of chromatin assembly and transcription. / Kadam, Shilpa; Emerson, Beverly.

In: Current Opinion in Cell Biology, Vol. 14, No. 3, 01.06.2002, p. 262-268.

Research output: Contribution to journalReview article

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