Abstract
Previous MRS measurements of ethanol in human brain have yielded a range of transverse relaxation times for ethanol methyl resonance at 1.5 T (200-380 ms). To determine the T2 of the methyl proton resonance of ethanol in human brain, 8 x 8 spectroscopic images were acquired at 16 different TE values. A frequency-selective refocusing pulse was used to suppress J-modulation of the ethanol triplet, permitting nonintegral multiples of 1/J to be used for TE values. The measured T2 values for the methyl resonances of ethanol, creatine, and N-acetyl aspartate in mixed tissues were 82 ± 12, 148 ± 20, and 227 ± 25 ms, respectively. Regression analysis of the measured T2 as a function of gray matter content indicates a shorter T2 value for ethanol in pure white matter compared to that in pure gray matter. (C) 2000 Wiley-Liss, Inc.
Original language | English (US) |
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Pages (from-to) | 35-40 |
Number of pages | 6 |
Journal | Magnetic Resonance in Medicine |
Volume | 44 |
Issue number | 1 |
DOIs | |
State | Published - 2000 |
Externally published | Yes |
Keywords
- Brain
- Ethanol
- Spectroscopy
- T
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging