@article{9ba785a0ce1d4d339444abf6d3666f2d,
title = "Measurement science in the circulatory system",
abstract = "The dynamics of the cellular and molecular constituents of the circulatory system are regulated by the biophysical properties of the heart, vasculature and blood cells and proteins. In this review, we discuss measurement techniques that have been developed to characterize the physical and mechanical parameters of the circulatory system across length scales ranging from the tissue scale (cm) to the molecular scale (nm) and time scales of years to milliseconds. We compare the utility of measurement techniques as a function of spatial resolution and penetration depth from both a diagnostic and research perspective. Together, this review provides an overview of the utility of measurement science techniques to study the spatial systems of the circulatory system in health and disease.",
keywords = "Blood, Microscopy, Physical parameters",
author = "Jones, {Casey M.} and Baker-Groberg, {Sandra M.} and Cianchetti, {Flor A.} and Glynn, {Jeremy J.} and Healy, {Laura D.} and Lam, {Wai Yan} and Nelson, {Jonathan W.} and Parrish, {Diana C.} and Phillips, {Kevin G.} and Scott-Drechsel, {Devon E.} and Tagge, {Ian J.} and Zelaya, {Jaime E.} and Hinds, {Monica T.} and McCarty, {Owen J.T.}",
note = "Funding Information: We are grateful to Juliana Porter for technical assistance. This work was supported by the National Institutes of Health (NIH) Grants U54CA143906 and R01HL101972 to O.J.T.M, R01HL095474 and R01HL103728 to M.T.H., R01HL101972-S1 to F.A.C, T32HL094294 to J.W.N., 5T32HL094294 to C.M.J., TL1TR000129 to J.Z., and the National Science Foundation (NSF) Grants DGE-0925180 to J.J.G. D.C.P. is supported by an OHSU Graduate Research Fellowship and NIH grant HL093056. W.Y.L. is supported by NIH grant R01NS071116. J.Z. is supported by NSF Grant DBI-1052688. S.M.B. is a Whitaker International Fellow. O.J.T.M. is an American Heart Association Established Investigator (13EIA12630000). W.Y.L. and J.J.G are ARCS Scholars.",
year = "2014",
month = mar,
doi = "10.1007/s12195-013-0317-4",
language = "English (US)",
volume = "7",
pages = "1--14",
journal = "Cellular and Molecular Bioengineering",
issn = "1865-5025",
publisher = "Springer New York",
number = "1",
}