Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry

Shao Pow Lin, Lihong Wang, Steven Jacques, Frank K. Tittel

Research output: Contribution to journalArticle

153 Citations (Scopus)

Abstract

Fiber-optic-based oblique-incidence reflectometry is a simple and accurate method for measuring the absorption and reduced scattering coefficients μa and μ′s of semi-infinite turbid media. Obliquely incident light produces a spatial distribution of diffuse reflectance that is not centered about the point of light entry. The amount of shift in the center of diffuse reflectance is directly related to the medium's diffusion length D. We developed a fiber-optic probe to deliver light obliquely and sample the relative profile of diffuse reflectance. Measurement in absolute units is not necessary. From the profile, it was possible to measure D, perform a curve fit for the effective attenuation coefficient μeff, and then calculate μa and μ′s. This method was verified with Monte Carlo simulations and tested on tissue phantoms. Our measurements of D and μeff had an accuracy of approximately 5%, thus giving us 10% and 5% accuracy for μa and μ′s, respectively.

Original languageEnglish (US)
Pages (from-to)136-143
Number of pages8
JournalApplied Optics
Volume36
Issue number1
StatePublished - Jan 1 1997
Externally publishedYes

Fingerprint

Optical fibers
Optical properties
incidence
optical fibers
Tissue
reflectance
optical properties
Fiber optics
fiber optics
scattering coefficients
attenuation coefficients
profiles
diffusion length
entry
Spatial distribution
spatial distribution
Scattering
probes
shift
curves

Keywords

  • Biomedical optics
  • Fiber optics
  • Oblique incidence
  • Optical properties
  • Reflectometry
  • Scattering media
  • Tissue optics
  • Turbid media

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Lin, S. P., Wang, L., Jacques, S., & Tittel, F. K. (1997). Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry. Applied Optics, 36(1), 136-143.

Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry. / Lin, Shao Pow; Wang, Lihong; Jacques, Steven; Tittel, Frank K.

In: Applied Optics, Vol. 36, No. 1, 01.01.1997, p. 136-143.

Research output: Contribution to journalArticle

Lin, SP, Wang, L, Jacques, S & Tittel, FK 1997, 'Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry', Applied Optics, vol. 36, no. 1, pp. 136-143.
Lin, Shao Pow ; Wang, Lihong ; Jacques, Steven ; Tittel, Frank K. / Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry. In: Applied Optics. 1997 ; Vol. 36, No. 1. pp. 136-143.
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