Measurement of hypothalamic corticotropin-releasing factors in hypophyseal portal blood

D. M. Gibbs

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Abstract

Among the putative hypothalamic hormones that can influence the release of adenocorticotropin (ACTH) in vitro, the 41-amino-acid corticotropin-releasing factor, oxytocin, vasopressin, and epinephrine were identified in hypophyseal portal plasma. Measurement of these substances in several situations associated with changes in ACTH secretion provided data consistent with a physiological role for all four hormones and suggested that control of the hypothalamo-hypophyseal-adrenal axis can be accomplished in different ways in response to different types of stimuli.

Original languageEnglish (US)
Pages (from-to)203-206
Number of pages4
JournalFederation Proceedings
Volume44
Issue number1 II
StatePublished - Jan 1 1985

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ASJC Scopus subject areas

  • Medicine(all)

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