Among the putative hypothalamic hormones that can influence the release of adenocorticotropin (ACTH) in vitro, the 41-amino-acid corticotropin-releasing factor, oxytocin, vasopressin, and epinephrine were identified in hypophyseal portal plasma. Measurement of these substances in several situations associated with changes in ACTH secretion provided data consistent with a physiological role for all four hormones and suggested that control of the hypothalamo-hypophyseal-adrenal axis can be accomplished in different ways in response to different types of stimuli.
|Original language||English (US)|
|Number of pages||4|
|Issue number||1 II|
|State||Published - Jan 1 1985|
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