Measure Twice: Promise of Liquid Biopsy in Pediatric High-Grade Gliomas

Matthew S. Dietz, Catherine Z. Beach, Ramon Barajas, Michael S. Parappilly, Sidharth K. Sengupta, Lissa C. Baird, Jeremy Ciporen, Seunggu J. Han, Rebecca Loret de Mola, Yoon Jae Cho, Kellie Nazemi, Shearwood McClelland, Melissa H. Wong, Jerry Jaboin

Research output: Contribution to journalReview article

Abstract

Purpose: To review and critique the current state of liquid biopsy in pHGG. Materials and Methods: Published literature was reviewed for articles related to liquid biopsy in pediatric glioma and adult glioma with a focus on high-grade gliomas. Results: This review discusses the current state of liquid biomarkers of pHGG and their potential applications for liquid biopsy development. Conclusions: While nascent, the progress toward identifying circulating analytes of pHGG primes the field of neuro-oncoogy for liquid biopsy development.

Original languageEnglish (US)
Pages (from-to)152-162
Number of pages11
JournalAdvances in Radiation Oncology
Volume5
Issue number2
DOIs
StatePublished - Mar 1 2020

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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