TY - JOUR
T1 - Maternal dietary fat intake during pregnancy and newborn body composition
AU - Damen, Natalie A.
AU - Gillingham, Melanie
AU - Hansen, Joyanna G.
AU - Thornburg, Kent L.
AU - Purnell, Jonathan Q.
AU - Marshall, Nicole E.
N1 - Funding Information:
Funding NEM is supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (grant number K23HD069520-01A1), and the Oregon Clinical and Translational Research Institute (UL1TR002369).
Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2021/5
Y1 - 2021/5
N2 - Objective: Increased infant birth weight and adiposity are associated with an altered risk of adult chronic diseases. The objective was to investigate the association between maternal dietary fat intake during pregnancy and newborn adiposity. Study design: The study included 79 singleton pregnancies. Associations between maternal dietary fat intake during each trimester and infant adiposity at birth were assessed. Result: Average total grams of maternal total dietary fat and unsaturated fat intake during pregnancy correlated with infant percent body fat after adjusting for potential confounding variables (r = 0.23, p = 0.045; r = 0.24, p = 0.037). Maternal average daily intake of total fat, saturated fat, and unsaturated fat during the second trimester of pregnancy were each associated with infant percent body fat (r = 0.25, p = 0.029; r = 0.23, p = 0.046; r = 0.25, p = 0.031; respectively). Conclusions: The second trimester of pregnancy is a key time period for fetal adipose tissue metabolic programming and therefore a target for nutritional intervention.
AB - Objective: Increased infant birth weight and adiposity are associated with an altered risk of adult chronic diseases. The objective was to investigate the association between maternal dietary fat intake during pregnancy and newborn adiposity. Study design: The study included 79 singleton pregnancies. Associations between maternal dietary fat intake during each trimester and infant adiposity at birth were assessed. Result: Average total grams of maternal total dietary fat and unsaturated fat intake during pregnancy correlated with infant percent body fat after adjusting for potential confounding variables (r = 0.23, p = 0.045; r = 0.24, p = 0.037). Maternal average daily intake of total fat, saturated fat, and unsaturated fat during the second trimester of pregnancy were each associated with infant percent body fat (r = 0.25, p = 0.029; r = 0.23, p = 0.046; r = 0.25, p = 0.031; respectively). Conclusions: The second trimester of pregnancy is a key time period for fetal adipose tissue metabolic programming and therefore a target for nutritional intervention.
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U2 - 10.1038/s41372-021-00922-0
DO - 10.1038/s41372-021-00922-0
M3 - Article
C2 - 33510420
AN - SCOPUS:85099942026
SN - 0743-8346
VL - 41
SP - 1007
EP - 1013
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 5
ER -