TY - JOUR
T1 - Maternal and paternal race/ethnicity are both associated with gestational diabetes
AU - Caughey, Aaron B.
AU - Cheng, Yvonne W.
AU - Stotland, Naomi E.
AU - Washington, A. Eugene
AU - Escobar, Gabriel J.
N1 - Funding Information:
This study was supported in part by Agency for Healthcare Research and Quality Grant 5 P01 HS10856-02 . A.B.C. is supported by the Robert Wood Johnson Foundation as Physician Faculty Scholar RWJF-61535 . N.E.S. is supported as a Women's Reproductive Health Research Scholar K12-HD001262 .
PY - 2010/6
Y1 - 2010/6
N2 - Objective: The objective of the study was to examine the rates of gestational diabetes mellitus (GDM) associated with both maternal and paternal race/ethnicity. Study Design: This was a retrospective cohort study of all women delivered within a managed care network. Rates of GDM were calculated for maternal, paternal, and combined race/ethnicity. Results: Among the 139,848 women with identified race/ethnicity, Asians had the highest rate (P < .001) of GDM (6.8%) as compared with whites (3.4%), African Americans (3.2%), and Hispanics (4.9%). When examining race/ethnicity controlling for potential confounders, we found that the rates of GDM were higher among Asian (adjusted odds ratio [aOR], 1.5; 95% confidence interval [CI], 1.4-1.6) and Hispanic (aOR, 1.2; 95% CI, 1.1-1.4) women as well as Asian (aOR, 1.4; 95% CI, 1.3-1.5) and Hispanic (aOR, 1.3; 95% CI, 1.2-1.4) men as compared with their white counterparts. Conclusion: We found that rates of GDM are affected by both maternal and paternal race/ethnicity. In both Asians and Hispanics, maternal and paternal race are equally associated with an increase in GDM. These differences may inform further investigation of the pathophysiology of GDM.
AB - Objective: The objective of the study was to examine the rates of gestational diabetes mellitus (GDM) associated with both maternal and paternal race/ethnicity. Study Design: This was a retrospective cohort study of all women delivered within a managed care network. Rates of GDM were calculated for maternal, paternal, and combined race/ethnicity. Results: Among the 139,848 women with identified race/ethnicity, Asians had the highest rate (P < .001) of GDM (6.8%) as compared with whites (3.4%), African Americans (3.2%), and Hispanics (4.9%). When examining race/ethnicity controlling for potential confounders, we found that the rates of GDM were higher among Asian (adjusted odds ratio [aOR], 1.5; 95% confidence interval [CI], 1.4-1.6) and Hispanic (aOR, 1.2; 95% CI, 1.1-1.4) women as well as Asian (aOR, 1.4; 95% CI, 1.3-1.5) and Hispanic (aOR, 1.3; 95% CI, 1.2-1.4) men as compared with their white counterparts. Conclusion: We found that rates of GDM are affected by both maternal and paternal race/ethnicity. In both Asians and Hispanics, maternal and paternal race are equally associated with an increase in GDM. These differences may inform further investigation of the pathophysiology of GDM.
KW - ethnicity
KW - gestational diabetes
KW - paternal
KW - race
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U2 - 10.1016/j.ajog.2010.01.082
DO - 10.1016/j.ajog.2010.01.082
M3 - Article
C2 - 20400060
AN - SCOPUS:77952746131
SN - 0002-9378
VL - 202
SP - 616.e1-616.e5
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 6
ER -