Maternal adaptation to pregnancy

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

Abstract

This chapter discusses several physiological changes that accompany pregnancy in women. Many adaptations of pregnancy are imperceptible even to the woman carrying a child, yet are essential for a successful pregnancy. An incomplete cardiovascular adaptation to pregnancy can lead to improper fetal development or even fetal demise. The average weight gain by women during pregnancy is approximately 12.5 kg and includes the increased weights of the fetus, amniotic fluid, uterine tissue, breast tissue, and blood, as well as extravascular and intracellular water. The maternal basal metabolic rate (BMR) also increases during pregnancy. BMR increases from approximately 1,300 kcals/day to approximately 1,700 kcal/day over gestation in women of average pre-pregnancy body mass index (BMI). Blood volume increases continuously from 6-8 weeks of gestation, reaches a maximum at approximately 32 to 34 weeks, and changes little thereafter. The increase in plasma volume (40%-50%) is relatively greater than that of red cell mass (20%-30%), resulting in a decrease in hemoglobin concentration. Moreover, whole-body remodeling of the maternal circulation begins within a few weeks of conception. Circulatory changes continue through parturition, when most of the changes are reversed.

Original languageEnglish (US)
Title of host publicationKnobil and Neill's Physiology of Reproduction
PublisherElsevier Inc.
Pages2899-2923
Number of pages25
ISBN (Print)9780125154000
DOIs
StatePublished - 2006

Fingerprint

Blood
Mothers
Tissue
Pregnancy
Hemoglobins
Cells
Plasmas
Fluids
Water
Basal Metabolism
Erythrocyte Volume
Fetal Death
Plasma Volume
Amniotic Fluid
Fetal Development
Blood Volume
Weight Gain
Breast
Body Mass Index
Fetus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Thornburg, K., Bagby, S., & Giraud, G. (2006). Maternal adaptation to pregnancy. In Knobil and Neill's Physiology of Reproduction (pp. 2899-2923). Elsevier Inc.. https://doi.org/10.1016/B978-012515400-0/50059-2

Maternal adaptation to pregnancy. / Thornburg, Kent; Bagby, Susan; Giraud, George.

Knobil and Neill's Physiology of Reproduction. Elsevier Inc., 2006. p. 2899-2923.

Research output: Chapter in Book/Report/Conference proceedingChapter

Thornburg, K, Bagby, S & Giraud, G 2006, Maternal adaptation to pregnancy. in Knobil and Neill's Physiology of Reproduction. Elsevier Inc., pp. 2899-2923. https://doi.org/10.1016/B978-012515400-0/50059-2
Thornburg K, Bagby S, Giraud G. Maternal adaptation to pregnancy. In Knobil and Neill's Physiology of Reproduction. Elsevier Inc. 2006. p. 2899-2923 https://doi.org/10.1016/B978-012515400-0/50059-2
Thornburg, Kent ; Bagby, Susan ; Giraud, George. / Maternal adaptation to pregnancy. Knobil and Neill's Physiology of Reproduction. Elsevier Inc., 2006. pp. 2899-2923
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