Markers of paradental tissue remodeling in the gingival crevicular fluid and saliva of orthodontic patients

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

This chapter presents an overview of the study of markers in oral fluids during orthodontic tooth movement (OTM) to date and prospects for the future. Both saliva and gingival crevicular fluid (GCF) are inexpensive potential sources of personalized oral and general health information. GCF studies associated with orthodontic tooth movement have so far been predominating compared to saliva studies. Furthermore, although GCF and saliva are expected to have similar constituents, concentrations are higher in GCF. Although the research to date implies that markers are important for assessing the effects of orthodontic therapy, improved diagnostic trials are needed before oral fluid markers can be useful as predictive or analytical clinical tools. The chapter outlines the variables that need to be addressed in future diagnostic trials by presenting an overview of the knowledge gained from and the limitations of the previous research with respect to these variables.

Original languageEnglish (US)
Title of host publicationBiological Mechanisms of Tooth Movement
Subtitle of host publicationSecond Edition
PublisherWiley-Blackwell
Pages138-144
Number of pages7
ISBN (Electronic)9781118916148
ISBN (Print)9781118688878
DOIs
StatePublished - Jun 26 2015
Externally publishedYes

Keywords

  • Diagnostic trials
  • Gingival crevicular fluid (GCF)
  • Oral fluid markers
  • Orthodontic tooth movement (OTM)
  • Saliva

ASJC Scopus subject areas

  • Dentistry(all)

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