Maribavir antagonizes the antiviral action of ganciclovir on human cytomegalovirus

Sunwen Chou, Gail I. Marousek

Research output: Contribution to journalArticle

65 Scopus citations

Abstract

The cytomegalovirus (CMV) UL97 kinase inhibitor maribavir antagonized the anti-CMV effect of ganciclovir, increasing the ganciclovir 50% inhibitory concentration against a sensitive strain by up to 13-fold. Antiviral activities of foscarnet and cidofovir were unaffected by maribavir.

Original languageEnglish (US)
Pages (from-to)3470-3472
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume50
Issue number10
DOIs
StatePublished - Oct 2006

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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