Mapping tissue optical attenuation to identify cancer using optical coherence tomography.

Robert A. McLaughlin, Loretta Scolaro, Peter Robbins, Christobel Saunders, Steven Jacques, David D. Sampson

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Citations (Scopus)

Abstract

The lymphatic system is a common route for the spread of cancer and the identification of lymph node metastases is a key task during cancer surgery. This paper demonstrates the use of optical coherence tomography to construct parametric images of lymph nodes. It describes a method to automatically estimate the optical attenuation coefficient of tissue. By mapping the optical attenuation coefficient at each location in the scan, it is possible to construct a parametric image indicating variations in tissue type. The algorithm is applied to ex vivo samples of human axillary lymph nodes and validated against a histological gold standard. Results are shown illustrating the variation in optical properties between cancerous and healthy tissue.

Original languageEnglish (US)
Title of host publicationMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Pages657-664
Number of pages8
Volume12
EditionPt 2
StatePublished - 2009

Fingerprint

Optical Coherence Tomography
Lymph Nodes
Lymphatic System
Neoplasms
Neoplasm Metastasis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

McLaughlin, R. A., Scolaro, L., Robbins, P., Saunders, C., Jacques, S., & Sampson, D. D. (2009). Mapping tissue optical attenuation to identify cancer using optical coherence tomography. In Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention (Pt 2 ed., Vol. 12, pp. 657-664)

Mapping tissue optical attenuation to identify cancer using optical coherence tomography. / McLaughlin, Robert A.; Scolaro, Loretta; Robbins, Peter; Saunders, Christobel; Jacques, Steven; Sampson, David D.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Vol. 12 Pt 2. ed. 2009. p. 657-664.

Research output: Chapter in Book/Report/Conference proceedingChapter

McLaughlin, RA, Scolaro, L, Robbins, P, Saunders, C, Jacques, S & Sampson, DD 2009, Mapping tissue optical attenuation to identify cancer using optical coherence tomography. in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 2 edn, vol. 12, pp. 657-664.
McLaughlin RA, Scolaro L, Robbins P, Saunders C, Jacques S, Sampson DD. Mapping tissue optical attenuation to identify cancer using optical coherence tomography. In Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 2 ed. Vol. 12. 2009. p. 657-664
McLaughlin, Robert A. ; Scolaro, Loretta ; Robbins, Peter ; Saunders, Christobel ; Jacques, Steven ; Sampson, David D. / Mapping tissue optical attenuation to identify cancer using optical coherence tomography. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Vol. 12 Pt 2. ed. 2009. pp. 657-664
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