MAP kinases

Zhu Chen, Tara Beers Gibson, Fred Robinson, Loraine Silvestro, Gray Pearson, Bing E. Xu, Angelique Wright, Colleen Vanderbilt, Melanie H. Cobb

Research output: Contribution to journalArticle

720 Scopus citations

Abstract

The regulation and functions of mammalian mitogen activated protein (MAP) kinases were studied. Various issues related to MAP kinases including control of localization, protein complexes and interactions with nuclear receptors were discussed. The disruption of a gene encoding and orphan MAP kinases like ERK3, ERK7, NLK and MOK were also described.

Original languageEnglish (US)
Pages (from-to)2449-2476
Number of pages28
JournalChemical Reviews
Volume101
Issue number8
DOIs
StatePublished - Aug 2001

ASJC Scopus subject areas

  • Chemistry(all)

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    Chen, Z., Gibson, T. B., Robinson, F., Silvestro, L., Pearson, G., Xu, B. E., Wright, A., Vanderbilt, C., & Cobb, M. H. (2001). MAP kinases. Chemical Reviews, 101(8), 2449-2476. https://doi.org/10.1021/cr000241p