Management of vascular perforations that occur during neurointerventional procedures

V. V. Halbach, R. T. Higashida, C. F. Dowd, S. L. Barnwell, G. B. Hieshima

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

This article describes a number of treatment strategies for the management of perforations that occur during neurointerventional procedures. During the past 5 years, we have performed over 1200 endovascular procedures to treat vascular disorders involving the brain and spinal cord (400 cerebral arteriovenous malformations, 230 tumors, 197 carotid cavernous fistulas, 183 aneurysms, 130 dural fistulas, 80 spinal arteriovenous malformations, 18 vein of Galen aneurysms, and 20 cases of vasospasm). Fifteen patients (1.1%) sustained a vascular perforation as a direct result of these procedures. Among these 15 patients, indications for endovascular treatment were six symptomatic arteriovenous malformations, two spinal cord arteriovenous malformations, two cavernous sinus dural fistulas, one transverse sinus fistula, one case of vasospasm following subarachnoid hemorrhage, one direct carotid cavernous fistula, one vein of Galen malformation, and one ruptured basilar artery aneurysm. The vascular perforations were grouped into three probable mechanisms: mechanical perforation of a normal vessel (six patients), mechanical disruption of a dysplastic vessel or aneurysm (five patients), and fluid overinjection (four patients). Treatment of the perforations included immediate reversal of anticoagulants (12 patients) and direct closure of the perforation site with coils (five patients). In addition, closure of the intravascular compartment adjacent to the perforation was achieved with coils (six patients), liquid adhesives (four patients), balloons (two patients), or particles (two patients). In two patients a detachable balloon was placed transiently across the perforation site for several minutes, deflated, and removed when no further extravasation was noted. Five patients were started on anticonvulsant therapy, two of whom have had a new onset seizure related to the perforation. Immediate consequences of the perforation induced headaches (nine patients), seizures (two patients), hydrocephalus (one patient), paraplegia (one patient), right upper extremity dysmetria (one patient), diabetes insipidus (two patients), and two deaths. One patient survived for 2 years without symptoms but died from unrelated causes. Long-term sequelae in the remaining 12 patients include diabetes insipidus in one and stable hydrocephalus in one. No documented episodes of rehemorrhage have occurred, and the patients were followed for a mean of 30 months. Despite the development of softer steerable guidewires and microcatheters, soft detachable balloons, and roadmapping techniques, vascular perforations may sometimes occur during endovascular procedures involving the brain and spinal cord. Prompt recognition and closure of the perforation is essential for a good outcome.

Original languageEnglish (US)
Pages (from-to)319-327
Number of pages9
JournalAmerican Journal of Neuroradiology
Volume12
Issue number2
StatePublished - 1991
Externally publishedYes

Fingerprint

Blood Vessels
Fistula
Arteriovenous Malformations
Spinal Cord
Endovascular Procedures
Diabetes Insipidus
Hydrocephalus
Aneurysm
Vein of Galen Malformations
Seizures
Transverse Sinuses
Intracranial Arteriovenous Malformations
Cerebrovascular Disorders
Cavernous Sinus
Cerebellar Ataxia
Ruptured Aneurysm
Paraplegia
Intracranial Aneurysm
Patient Rights
Subarachnoid Hemorrhage

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Halbach, V. V., Higashida, R. T., Dowd, C. F., Barnwell, S. L., & Hieshima, G. B. (1991). Management of vascular perforations that occur during neurointerventional procedures. American Journal of Neuroradiology, 12(2), 319-327.

Management of vascular perforations that occur during neurointerventional procedures. / Halbach, V. V.; Higashida, R. T.; Dowd, C. F.; Barnwell, S. L.; Hieshima, G. B.

In: American Journal of Neuroradiology, Vol. 12, No. 2, 1991, p. 319-327.

Research output: Contribution to journalArticle

Halbach, VV, Higashida, RT, Dowd, CF, Barnwell, SL & Hieshima, GB 1991, 'Management of vascular perforations that occur during neurointerventional procedures', American Journal of Neuroradiology, vol. 12, no. 2, pp. 319-327.
Halbach VV, Higashida RT, Dowd CF, Barnwell SL, Hieshima GB. Management of vascular perforations that occur during neurointerventional procedures. American Journal of Neuroradiology. 1991;12(2):319-327.
Halbach, V. V. ; Higashida, R. T. ; Dowd, C. F. ; Barnwell, S. L. ; Hieshima, G. B. / Management of vascular perforations that occur during neurointerventional procedures. In: American Journal of Neuroradiology. 1991 ; Vol. 12, No. 2. pp. 319-327.
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