Management of the "violated Neck" in the era of chemoradiation

Myriam Loyo, Jonas T. Johnson, William H. Westra, Simion I. Chiosea, Christine G. Gourin

Research output: Contribution to journalArticle

5 Scopus citations


Objectives: To determine if patients who have undergone an open neck biopsy (a "violated" neck) have improved disease control and survival with completion neck dissection. Materials and Methods: Retrospective review of patients who underwent open cervical biopsy for diagnosis prior to definitive treatment between February 1997 and February 2010 at two academic tertiary referral centers. Results: Ninety-four patients met study criteria, with completion neck dissection performed in 53 patients (56%). The majority of patients (84%) had oropharyngeal tumors. Human papilloma virus (HPV) status was positive in 55 of 63 patients (87%). Chemotherapy was used more often in patients treated nonoperatively (88%) compared to patients who underwent neck dissection (49%; P

Original languageEnglish (US)
Pages (from-to)2349-2358
Number of pages10
Issue number11
Publication statusPublished - Nov 2011
Externally publishedYes



  • cervical biopsy
  • Cervical metastases
  • Level of Evidence: 2b.
  • neck dissection
  • radiation
  • squamous cell cancer
  • surgery
  • violated neck

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Loyo, M., Johnson, J. T., Westra, W. H., Chiosea, S. I., & Gourin, C. G. (2011). Management of the "violated Neck" in the era of chemoradiation. Laryngoscope, 121(11), 2349-2358.