Mammalian two-hybrid assay for detecting protein-protein interactions in vivo.

Research output: Contribution to journalReview article

18 Scopus citations

Abstract

Mammalian two-hybrid assay is a convenient, powerful tool to investigate protein-protein interactions in vivo. In particular, this method has a major advantage over the better known yeast version in that one can study interactions between mammalian proteins that may not fold correctly in yeast or that require post-translational modification or external stimulation that are not present in yeast.

Original languageEnglish (US)
Pages (from-to)327-336
Number of pages10
JournalMethods in molecular biology (Clifton, N.J.)
Volume261
StatePublished - 2004

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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