Abstract
Mammalian two-hybrid assay is a convenient, powerful tool to investigate protein-protein interactions in vivo. In particular, this method has a major advantage over the better known yeast version in that one can study interactions between mammalian proteins that may not fold correctly in yeast or that require post-translational modification or external stimulation that are not present in yeast.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 327-336 |
| Number of pages | 10 |
| Journal | Methods in molecular biology (Clifton, N.J.) |
| Volume | 261 |
| State | Published - 2004 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics