Abstract
Mammalian two-hybrid assay is a convenient, powerful tool to investigate protein-protein interactions in vivo. In particular, this method has a major advantage over the better known yeast version in that one can study interactions between mammalian proteins that may not fold correctly in yeast or that require post-translational modification or external stimulation that are not present in yeast.
Original language | English (US) |
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Pages (from-to) | 327-336 |
Number of pages | 10 |
Journal | Methods in molecular biology (Clifton, N.J.) |
Volume | 261 |
DOIs | |
State | Published - 2004 |
ASJC Scopus subject areas
- Molecular Biology
- Genetics