Mammalian two-hybrid assay is a convenient, powerful tool to investigate protein-protein interactions in vivo. In particular, this method has a major advantage over the better known yeast version in that one can study interactions between mammalian proteins that may not fold correctly in yeast or that require post-translational modification or external stimulation that are not present in yeast.
|Original language||English (US)|
|Number of pages||10|
|Journal||Methods in molecular biology (Clifton, N.J.)|
|State||Published - 2004|
ASJC Scopus subject areas
- Molecular Biology