Malignant eccrine poroma. Case report and review of the literature

K. Bottles, R. W. Sagebiel, N. S. McNutt, B. Jensen, Karen Deveney

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

A case of malignant eccrine poroma with lymph node metastases is described. The patient had a nodular growth of the right thigh 2 years before its first excision. Local recurrence in the scar occurred in 6 months, and by 8 months a right groin lymph node was involved. Subsequent skin nodules of the right thigh occurred over the next 12 months, associated with recurrent lymphedema of the leg. During several follow-up visits, associated malignancies were found including villous adenoma of the ascending colon and renal cell carcinoma of the right kidney, both typical histologically and unrelated to the cutaneous tumor. Subsequently, left inguinal lymph node disease histologically identical to the skin tumor was found. Clinical and histologic findings were similar to the 31 previous cases reviewed. Electron microscopic examination confirmed the presence of a ductal structure consistent with eccrine duct and a crystalline membrane-bound granule which may represent a specific marker for this rare tumor. The histologic features of this tumor are important to separate from other differential diagnostic possibilities which may have a quite different prognosis.

Original languageEnglish (US)
Pages (from-to)1579-1585
Number of pages7
JournalCancer
Volume53
Issue number7
DOIs
StatePublished - 1984
Externally publishedYes

Fingerprint

Eccrine Porocarcinoma
Groin
Lymph Nodes
Thigh
Skin
Neoplasms
Villous Adenoma
Ascending Colon
Lymphedema
Tumor Biomarkers
Renal Cell Carcinoma
Cicatrix
Leg
Electrons
Neoplasm Metastasis
Kidney
Recurrence
Membranes
Growth

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Malignant eccrine poroma. Case report and review of the literature. / Bottles, K.; Sagebiel, R. W.; McNutt, N. S.; Jensen, B.; Deveney, Karen.

In: Cancer, Vol. 53, No. 7, 1984, p. 1579-1585.

Research output: Contribution to journalArticle

Bottles, K. ; Sagebiel, R. W. ; McNutt, N. S. ; Jensen, B. ; Deveney, Karen. / Malignant eccrine poroma. Case report and review of the literature. In: Cancer. 1984 ; Vol. 53, No. 7. pp. 1579-1585.
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