Major bile duct injury requiring operative reconstruction after laparoscopic cholecystectomy: a follow-on study

Patrick J. Worth, Taranjeet Kaur, Brian S. Diggs, Brett C. Sheppard, John G. Hunter, James Dolan

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Background: Bile duct injury (BDI) after laparoscopic cholecystectomy (LC) has significant cost impact and is a significant source of morbidity and mortality. We undertook a population-based assessment of the national experience with BDI between 2001 and 2011 and compared this to our report for the prior decade. Methods: Using the nationwide inpatient sample (NIS) for 2001–2011, we identified patients who underwent LC or partial cholecystectomy, with and without biliary reconstruction. Data were analyzed using methods that accounted for the hierarchical, stratified random sampling of the NIS. Both univariate modeling and multivariate modeling were performed. Results: LCs increased from 71.1 % in 2001 to 79.0 % in 2011 (p < 0.0001). Annual mortality decreased from 0.56 to 0.38 % (p = 0.002). In 2001, 0.11 % of LCs were associated with biliary reconstruction versus 0.09 % in 2011 (p = 0.15) with rates ranging from 0.08 to 0.12 %. The need for reconstruction was associated with an average in-hospital mortality rate of 4.4 %. Mortality rates from LC remained consistent across the study period (average mortality, 0.10 %, p = 0.57). Under multivariate analysis, admission to rural or urban non-teaching centers was associated with a decreased rate of injury; the majority of major BDIs were admitted from clinic or outpatient settings. These results are consistent with results from the prior decade. Neither emergent admission nor race was associated with increased odds of BDI, and this differs from our prior analysis. Conclusion: LC continued to increase in utilization between 2001 and 2011. Although rates of BDI have decreased, the need for reconstruction continues to be associated with a significant mortality. In addition, mortality related to biliary reconstruction is also higher than previously published series and may reflect the complexity of managing biliary injury as well as the higher likelihood of these patients having comorbid conditions.

Original languageEnglish (US)
Pages (from-to)1839-1846
Number of pages8
JournalSurgical endoscopy
Issue number5
StatePublished - May 1 2016


  • Bile duct injury
  • Laparoscopic cholecystectomy
  • Trends

ASJC Scopus subject areas

  • Surgery


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