Magnetic resonance spectroscopic imaging of benign prostatic tissue: Findings at 3.0 T compared to 1.5 T-initial experience

Munish Chitkara, Antonio Westphalen, John Kurhanewicz, Aliya Qayyum, Liina Poder, Galen Reed, Fergus V. Coakley

Research output: Contribution to journalArticle

6 Scopus citations


In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.

Original languageEnglish (US)
Pages (from-to)288-293
Number of pages6
JournalClinical Imaging
Issue number4
StatePublished - Jul 1 2011



  • 3 T
  • Cancer
  • MR
  • MR spectroscopy
  • Prostate

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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