Magnetic resonance spectroscopic imaging of benign prostatic tissue: Findings at 3.0 T compared to 1.5 T-initial experience

Munish Chitkara; Antonio Westphalen; John Kurhanewicz; Aliya Qayyum; Liina Poder; Galen Reed; Fergus V. Coakley

doi:10.1016/j.clinimag.2010.07.005

Magnetic resonance spectroscopic imaging of benign prostatic tissue: Findings at 3.0 T compared to 1.5 T-initial experience

Munish Chitkara, Antonio Westphalen, John Kurhanewicz, Aliya Qayyum, Liina Poder, Galen Reed, Fergus V. Coakley

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.

Original language	English (US)
Pages (from-to)	288-293
Number of pages	6
Journal	Clinical Imaging
Volume	35
Issue number	4
DOIs	https://doi.org/10.1016/j.clinimag.2010.07.005
State	Published - Jul 2011
Externally published	Yes

Keywords

3 T
Cancer
MR
MR spectroscopy
Prostate

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2010.07.005

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title = "Magnetic resonance spectroscopic imaging of benign prostatic tissue: Findings at 3.0 T compared to 1.5 T-initial experience",

abstract = "In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.",

keywords = "3 T, Cancer, MR, MR spectroscopy, Prostate",

author = "Munish Chitkara and Antonio Westphalen and John Kurhanewicz and Aliya Qayyum and Liina Poder and Galen Reed and Coakley, {Fergus V.}",

year = "2011",

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T2 - Findings at 3.0 T compared to 1.5 T-initial experience

AU - Chitkara, Munish

AU - Westphalen, Antonio

AU - Kurhanewicz, John

AU - Qayyum, Aliya

AU - Poder, Liina

AU - Reed, Galen

AU - Coakley, Fergus V.

PY - 2011/7

Y1 - 2011/7

N2 - In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.

AB - In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.

KW - 3 T

KW - Cancer

KW - MR

KW - MR spectroscopy

KW - Prostate

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ER -

Magnetic resonance spectroscopic imaging of benign prostatic tissue: Findings at 3.0 T compared to 1.5 T-initial experience

Abstract

Keywords

ASJC Scopus subject areas

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