Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery

Engineering & Materials Science

• Silica nanoparticles 100%
• Polyethylene glycols 85%
• Antibodies 83%
• RNA 79%
• Nanoparticles 65%
• Polymers 48%
• Drying 28%
• Bioactivity 19%
• Freezing 15%
• Trehalose 13%
• Inorganic polymers 12%
• Personalized medicine 10%
• Lipids 9%
• Physicochemical properties 9%
• Copolymers 8%
• Phosphates 8%
• Chemical properties 8%
• Cells 7%
• Genes 7%
• Physical properties 6%
• Hydrodynamics 6%
• Temperature 5%

Medicine & Life Sciences

• Freeze Drying 84%
• Silicon Dioxide 75%
• Polymers 58%
• Nanoparticles 58%
• Small Interfering RNA 55%
• Antibodies 36%
• Freezing 13%
• Temperature 9%
• Tromethamine 9%
• Trehalose 9%
• Polyethyleneimine 8%
• Hydrodynamics 7%
• Precision Medicine 7%
• Gene Silencing 7%
• Buffers 6%
• Phosphates 5%
• Lipids 4%
• Neoplasms 2%
• Therapeutics 1%

Chemical Compounds

• Small Interfering RNA 91%
• Nanoparticle 33%
• Inorganic Nanoparticle 20%
• Bioactivity 11%
• Buffer Solution 10%
• Trehalose 10%
• Freeze Drying 9%
• Hydrodynamics 7%
• Time 5%
• Lipid 5%
• Copolymer 5%
• Aqueous Solution 4%
• Application 2%