Lung cancer stage at diagnosis: Individual associations in the prospective VITamins and lifestyle (VITAL) cohort

Christopher G. Slatore, Michael K. Gould, David H. Au, Mark E. Deffebach, Emily White

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Lung cancer is the leading cause of cancer death in the United States. Identifying factors associated with stage of diagnosis can improve our understanding of biologic and behavioral pathways of lung cancer development and detection. We used data from a prospective cohort study to evaluate associations of demographic, health history, and health behaviors with early versus late stage at diagnosis of non-small cell lung cancer (NSCLC).Methods: We calculated odds ratios (ORs) for the association of patient-level characteristics with advanced stage of diagnosis for NSCLC. The OR's were then adjusted for age, gender, race/ethnicity, smoking status, income, education, chronic obstructive pulmonary disease, and a comorbidity index.Results: We identified 612 cases of NSCLC among 77,719 adults, aged 50 to 76 years from Washington State recruited in 2000-2002, with followup through December 2007. In univariate analyses, subjects who quit smoking

Original languageEnglish (US)
Article number228
JournalBMC Cancer
Volume11
DOIs
StatePublished - Jun 7 2011

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Vitamins
Non-Small Cell Lung Carcinoma
Life Style
Lung Neoplasms
Smoking
Health Behavior
Chronic Obstructive Pulmonary Disease
Comorbidity
Cause of Death
Cohort Studies
Odds Ratio
Demography
Prospective Studies
Education
Health
Neoplasms

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Genetics

Cite this

Lung cancer stage at diagnosis : Individual associations in the prospective VITamins and lifestyle (VITAL) cohort. / Slatore, Christopher G.; Gould, Michael K.; Au, David H.; Deffebach, Mark E.; White, Emily.

In: BMC Cancer, Vol. 11, 228, 07.06.2011.

Research output: Contribution to journalArticle

Slatore, Christopher G. ; Gould, Michael K. ; Au, David H. ; Deffebach, Mark E. ; White, Emily. / Lung cancer stage at diagnosis : Individual associations in the prospective VITamins and lifestyle (VITAL) cohort. In: BMC Cancer. 2011 ; Vol. 11.
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