Abstract
Sudden Cardiac Death. Introduction: Sudden cardiac death (SCD) is a large public health problem that warrants on-going evaluation in the general population. While single-year community-based studies have been performed there is a lack of studies that have extended evaluation to multiple years in the same community. Methods and Results: From the on-going Oregon Sudden Unexpected Death Study, we analyzed prospectively identified SCD cases in Multnomah County, Ore, (population ≈700,000) from February 1, 2002 to January 31, 2005. Detailed information ascertained from multiple sources (first responders, clinical records, and medical examiner) was analyzed. A total of 1,175 SCD cases were identified (61% male) with a mean age of 65 ± 18 years for men versus 70 ± 20 for women (P <0.001). The overall incidence rate for the period was 58/100,000 residents/year. One-quarter (24.6%) was ≤55 years of age. The most common initial rhythm was ventricular tachycardia or fibrillation (39% of cases, survival 27%) followed by asystole (36%, survival 0.7%) and pulseless electrical activity (23%, survival 6%). Among subjects that underwent resuscitation, the rate of survival to hospital discharge was 12% and overall survival to hospital discharge irrespective of resuscitation was 8%. Of the 68 survivors, 16 (24%) received a secondary prevention ICD. Conclusion: We report annualized SCD incidence from a multiple-year, multiple-source community-based study, with higher than expected rates of women and subjects age ≤55 years. The low implantation rate of secondary prevention ICDs is likely to be multifactorial, but there are potential implications for recalibration of the projected need for ICD implantation; larger and more detailed studies are warranted.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 60-65 |
| Number of pages | 6 |
| Journal | Journal of Cardiovascular Electrophysiology |
| Volume | 24 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2013 |
Fingerprint
Keywords
- cardiac arrest
- cardiopulmonary resuscitation
- implantable cardioverter defibrillator
- sudden cardiac death
- ventricular fibrillation
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Physiology (medical)
Cite this
Low rate of secondary prevention ICDs in the general population : Multiple-year multiple-source surveillance of sudden cardiac death in the Oregon Sudden Unexpected Death Study. / Havmoeller, Rasmus; Reinier, Kyndaron; Teodorescu, Carmen; Uy-Evanado, Audrey; Mariani, Ronald; Gunson, Karen; Jui, Jonathan; Chugh, Sumeet S.
In: Journal of Cardiovascular Electrophysiology, Vol. 24, No. 1, 01.2013, p. 60-65.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Low rate of secondary prevention ICDs in the general population
T2 - Multiple-year multiple-source surveillance of sudden cardiac death in the Oregon Sudden Unexpected Death Study
AU - Havmoeller, Rasmus
AU - Reinier, Kyndaron
AU - Teodorescu, Carmen
AU - Uy-Evanado, Audrey
AU - Mariani, Ronald
AU - Gunson, Karen
AU - Jui, Jonathan
AU - Chugh, Sumeet S.
PY - 2013/1
Y1 - 2013/1
N2 - Sudden Cardiac Death. Introduction: Sudden cardiac death (SCD) is a large public health problem that warrants on-going evaluation in the general population. While single-year community-based studies have been performed there is a lack of studies that have extended evaluation to multiple years in the same community. Methods and Results: From the on-going Oregon Sudden Unexpected Death Study, we analyzed prospectively identified SCD cases in Multnomah County, Ore, (population ≈700,000) from February 1, 2002 to January 31, 2005. Detailed information ascertained from multiple sources (first responders, clinical records, and medical examiner) was analyzed. A total of 1,175 SCD cases were identified (61% male) with a mean age of 65 ± 18 years for men versus 70 ± 20 for women (P <0.001). The overall incidence rate for the period was 58/100,000 residents/year. One-quarter (24.6%) was ≤55 years of age. The most common initial rhythm was ventricular tachycardia or fibrillation (39% of cases, survival 27%) followed by asystole (36%, survival 0.7%) and pulseless electrical activity (23%, survival 6%). Among subjects that underwent resuscitation, the rate of survival to hospital discharge was 12% and overall survival to hospital discharge irrespective of resuscitation was 8%. Of the 68 survivors, 16 (24%) received a secondary prevention ICD. Conclusion: We report annualized SCD incidence from a multiple-year, multiple-source community-based study, with higher than expected rates of women and subjects age ≤55 years. The low implantation rate of secondary prevention ICDs is likely to be multifactorial, but there are potential implications for recalibration of the projected need for ICD implantation; larger and more detailed studies are warranted.
AB - Sudden Cardiac Death. Introduction: Sudden cardiac death (SCD) is a large public health problem that warrants on-going evaluation in the general population. While single-year community-based studies have been performed there is a lack of studies that have extended evaluation to multiple years in the same community. Methods and Results: From the on-going Oregon Sudden Unexpected Death Study, we analyzed prospectively identified SCD cases in Multnomah County, Ore, (population ≈700,000) from February 1, 2002 to January 31, 2005. Detailed information ascertained from multiple sources (first responders, clinical records, and medical examiner) was analyzed. A total of 1,175 SCD cases were identified (61% male) with a mean age of 65 ± 18 years for men versus 70 ± 20 for women (P <0.001). The overall incidence rate for the period was 58/100,000 residents/year. One-quarter (24.6%) was ≤55 years of age. The most common initial rhythm was ventricular tachycardia or fibrillation (39% of cases, survival 27%) followed by asystole (36%, survival 0.7%) and pulseless electrical activity (23%, survival 6%). Among subjects that underwent resuscitation, the rate of survival to hospital discharge was 12% and overall survival to hospital discharge irrespective of resuscitation was 8%. Of the 68 survivors, 16 (24%) received a secondary prevention ICD. Conclusion: We report annualized SCD incidence from a multiple-year, multiple-source community-based study, with higher than expected rates of women and subjects age ≤55 years. The low implantation rate of secondary prevention ICDs is likely to be multifactorial, but there are potential implications for recalibration of the projected need for ICD implantation; larger and more detailed studies are warranted.
KW - cardiac arrest
KW - cardiopulmonary resuscitation
KW - implantable cardioverter defibrillator
KW - sudden cardiac death
KW - ventricular fibrillation
UR - http://www.scopus.com/inward/record.url?scp=84871993784&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871993784&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8167.2012.02407.x
DO - 10.1111/j.1540-8167.2012.02407.x
M3 - Article
C2 - 22860692
AN - SCOPUS:84871993784
VL - 24
SP - 60
EP - 65
JO - Journal of Cardiovascular Electrophysiology
JF - Journal of Cardiovascular Electrophysiology
SN - 1045-3873
IS - 1
ER -