Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population

Caterina Vacchi-Suzzi, Roxanne Karimi, Danielle Kruse, Susan M. Silbernagel, Keith E. Levine, Diane Rohlman, Jaymie R. Meliker

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Neurodevelopmental effects of omega-3 fatty acids and mercury from fish consumption have been characterized in children. In contrast, neurobehavioral outcomes associated with fish are not well studied in adults. Objective: This study of avid seafood consumers on Long Island (NY, USA) sought to define associations between mercury, seafood consumption, omega-3 fatty acids and neurobehavioral outcomes. Methods: A computer-based test system was used to assess neurobehavioral function. Blood total Hg (Hg) and omega-3 index were measured in 199 adult avid seafood eaters, who also completed the neurobehavioral assessment and an extensive food and fish frequency and demographic questionnaire. Results: For most of the outcomes considered, neither Hg nor omega-3 index was associated with neurobehavioral outcomes after adjustment for key confounding variables. Fish consumption, however, was associated with decreased odds of both self-reported fatigue (OR 0.85; 95 % CI 0.72, 1.01) and a constellation of neurologic symptoms (OR 0.79; 95 % CI 0.66, 0.96). Conclusions: Results from our study provide little evidence that omega-3 fatty acids or Hg is associated with cognitive function in adult avid seafood consumers. Larger studies are needed to confirm our finding of associations between fish consumption and decreased self-reported fatigue and neurologic impairment.

Original languageEnglish (US)
Pages (from-to)699-711
Number of pages13
JournalEuropean Journal of Nutrition
Volume55
Issue number2
DOIs
StatePublished - Mar 1 2016

Fingerprint

Seafood
Mercury
Fishes
Omega-3 Fatty Acids
Population
Fatigue
Confounding Factors (Epidemiology)
Neurologic Manifestations
Islands
Cognition
Nervous System
Demography
Food

Keywords

  • Mercury
  • Methylmercury
  • n-3 fatty acids
  • Neurobehavioral test
  • Neurological test
  • Omega-3

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Vacchi-Suzzi, C., Karimi, R., Kruse, D., Silbernagel, S. M., Levine, K. E., Rohlman, D., & Meliker, J. R. (2016). Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population. European Journal of Nutrition, 55(2), 699-711. https://doi.org/10.1007/s00394-015-0890-5

Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population. / Vacchi-Suzzi, Caterina; Karimi, Roxanne; Kruse, Danielle; Silbernagel, Susan M.; Levine, Keith E.; Rohlman, Diane; Meliker, Jaymie R.

In: European Journal of Nutrition, Vol. 55, No. 2, 01.03.2016, p. 699-711.

Research output: Contribution to journalArticle

Vacchi-Suzzi, C, Karimi, R, Kruse, D, Silbernagel, SM, Levine, KE, Rohlman, D & Meliker, JR 2016, 'Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population', European Journal of Nutrition, vol. 55, no. 2, pp. 699-711. https://doi.org/10.1007/s00394-015-0890-5
Vacchi-Suzzi, Caterina ; Karimi, Roxanne ; Kruse, Danielle ; Silbernagel, Susan M. ; Levine, Keith E. ; Rohlman, Diane ; Meliker, Jaymie R. / Low-level mercury, omega-3 index and neurobehavioral outcomes in an adult US coastal population. In: European Journal of Nutrition. 2016 ; Vol. 55, No. 2. pp. 699-711.
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