The ability of adherent target cells to remain attached to their substratum is lost as an early consequence of interaction with cytotoxic T lymphocytes. This phenomenon is shown to be a distinct event in the lytic process induced by cytotoxic T lymphocytes and does not occur during lysis by antibody plus complement. Thus loss of adhesion represent a previously unrecognized form of immune damage which may have important implications in both normal and pathologic responses.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of Immunology|
|State||Published - 1988|
ASJC Scopus subject areas
- Immunology and Allergy