Two pediatric patients with diffuse pontine tumors underwent MR spectroscopic imaging pre- and postradiation. Choline/creatine (Cho/Cr) and Cho/N-acetylaspartate (NAA) ratios were elevated before treatment, with no MR imaging contrast enhancement. These ratios were further elevated at 2 posttreatment follow-up studies, despite signs of excellent clinical improvement at initial follow-up. This study suggests that MR spectroscopic imaging is more specific in assessing the aggressiveness of diffuse pontine tumors than conventional MR imaging and can serve as a valuable tool in early prognostication.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Neuroradiology|
|State||Published - Apr 1 2006|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology