Long-term outcomes of septal reduction for obstructive hypertrophic cardiomyopathy

Daniel Sedehi, Gherardo Finocchiaro, Yen Tibayan, Jeffrey Chi, Aleksandra Pavlovic, Young M. Kim, Frederick (Fred) Tibayan, Bruce A. Reitz, Robert C. Robbins, Joseph Woo, Richard Ha, David P. Lee, Euan A. Ashley

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Surgical myectomy and alcohol septal ablation (ASA) aim to decrease left ventricular outflow tract (LVOT) gradient in hypertrophic cardiomyopathy (HCM). Outcome of myectomy beyond 10 years has rarely been described. We describe 20 years of follow-up of surgical myectomy and 5 years of follow-up for ASA performed for obstructive HCM. Methods: We studied 171 patients who underwent myectomy for symptomatic LVOT obstruction between 1972 and 2006. In addition, we studied 52 patients who underwent ASA for the same indication and who declined surgery. Follow-up of New York Heart Association (NYHA) functional class, echocardiographic data, and vital status were obtained from patient records. Mortality rates were compared with expected mortality rates of age- and sex-matched populations. Results: Surgical myectomy improved NYHA class (2.74 ± 0.65 to 1.54 ± 0.74, p<0.001), reduced resting gradient (67.4 ± 43.4 mmHg to 11.2. ± 16.4 mmHg, p

Original languageEnglish (US)
Pages (from-to)57-62
Number of pages6
JournalJournal of Cardiology
Volume66
Issue number1
DOIs
StatePublished - Jul 1 2015
Externally publishedYes

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Hypertrophic Cardiomyopathy
Alcohols
Ventricular Outflow Obstruction
Mortality
Population

Keywords

  • Alcohol septal ablation
  • Hypertrophic cardiomyopathy
  • Long-term outcomes
  • Septal myectomy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Long-term outcomes of septal reduction for obstructive hypertrophic cardiomyopathy. / Sedehi, Daniel; Finocchiaro, Gherardo; Tibayan, Yen; Chi, Jeffrey; Pavlovic, Aleksandra; Kim, Young M.; Tibayan, Frederick (Fred); Reitz, Bruce A.; Robbins, Robert C.; Woo, Joseph; Ha, Richard; Lee, David P.; Ashley, Euan A.

In: Journal of Cardiology, Vol. 66, No. 1, 01.07.2015, p. 57-62.

Research output: Contribution to journalArticle

Sedehi, D, Finocchiaro, G, Tibayan, Y, Chi, J, Pavlovic, A, Kim, YM, Tibayan, FF, Reitz, BA, Robbins, RC, Woo, J, Ha, R, Lee, DP & Ashley, EA 2015, 'Long-term outcomes of septal reduction for obstructive hypertrophic cardiomyopathy', Journal of Cardiology, vol. 66, no. 1, pp. 57-62. https://doi.org/10.1016/j.jjcc.2014.08.010
Sedehi, Daniel ; Finocchiaro, Gherardo ; Tibayan, Yen ; Chi, Jeffrey ; Pavlovic, Aleksandra ; Kim, Young M. ; Tibayan, Frederick (Fred) ; Reitz, Bruce A. ; Robbins, Robert C. ; Woo, Joseph ; Ha, Richard ; Lee, David P. ; Ashley, Euan A. / Long-term outcomes of septal reduction for obstructive hypertrophic cardiomyopathy. In: Journal of Cardiology. 2015 ; Vol. 66, No. 1. pp. 57-62.
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