Long-term optical imaging of intrinsic signals in anesthetized and awake monkeys

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Some exciting new efforts to use intrinsic signal optical imaging methods for long-term studies in anesthetized and awake monkeys are reviewed. The development of such methodologies opens the door for studying behavioral states such as attention, motivation, memory, emotion, and other higher-order cognitive functions. Long-term imaging is also ideal for studying changes in the brain that accompany development, plasticity, and learning. Although intrinsic imaging lacks the temporal resolution offered by dyes, it is a high spatial resolution imaging method that does not require application of any external agents to the brain. The bulk of procedures described here have been developed in the monkey but can be applied to the study of surface structures in any in vivo preparation.

Original languageEnglish (US)
Pages (from-to)1872-1880
Number of pages9
JournalApplied Optics
Volume46
Issue number10
DOIs
StatePublished - Apr 1 2007
Externally publishedYes

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monkeys
brain
emotions
Imaging techniques
temporal resolution
plastic properties
learning
optical communication
Brain
spatial resolution
dyes
methodology
preparation
high resolution
Surface structure
Plasticity
Dyes
Data storage equipment

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Long-term optical imaging of intrinsic signals in anesthetized and awake monkeys. / Roe, Anna.

In: Applied Optics, Vol. 46, No. 10, 01.04.2007, p. 1872-1880.

Research output: Contribution to journalArticle

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