Long-term humoral immunity against viruses: Revisiting the issue of plasma cell longevity

Mark K. Slifka, Rafi Ahmed

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations

Abstract

Despite extensive documentation of prolonged antibody responses following vaccination or acute viral infection, the mechanisms behind long-term antibody production are not fully understood. We propose the hypothesis that long-lived plasma cells are an important, yet largely overlooked, component of long-term humoral immunity.

Original languageEnglish (US)
Pages (from-to)394-400
Number of pages7
JournalTrends in microbiology
Volume4
Issue number10
DOIs
StatePublished - Oct 1996
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

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